SCHEMBL20657261

SCHEMBL20657261

CC=CC(=O)NCCCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
POLB P06746 2/20 0.49
ALDH1A1 P00352 2/20 0.49
MEN1 O00255 2/20 0.49
MAPT P10636 2/20 0.49
KDM4E B2RXH2 2/20 0.49
CACNA1B Q00975 1/20 0.49
APBA1 Q02410 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ADRA1A P35348 1/20 0.47
PRMT1 Q99873 1/20 0.45
PLA2G4A P47712 1/20 0.43
APEX1 P27695 1/20 0.43
TAAR1 Q96RJ0 1/20 0.41
SLC6A5 Q9Y345 1/20 0.41
EPHX2 P34913 5/20 0.40
HTT P42858 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28459307 1.00 KMT2A (0.49) KMT2APOLBALDH1A1MEN1MAPT
SCHEMBL20657255 0.94 ADRA1A (0.55) KMT2APOLBALDH1A1MEN1MAPT
SCHEMBL22200049 0.92 ADRA1A (0.58) POLBADRA1APRMT1PLA2G4AAPEX1
SCHEMBL9829252 0.92 ADRA1A (0.58) POLBADRA1APRMT1PLA2G4AAPEX1
SCHEMBL28416594 0.92 ADRA1A (0.58) POLBADRA1APRMT1PLA2G4AAPEX1
SCHEMBL9829255 0.92 ADRA1A (0.58) POLBADRA1APRMT1PLA2G4AAPEX1
SCHEMBL20657235 0.88 ECE1 (0.42) KMT2APOLBALDH1A1MEN1MAPT
SCHEMBL19272321 0.85 CNR2 (0.46) KMT2APOLBALDH1A1MEN1MAPT
SCHEMBL21610956 0.85 APEX1 (0.49) KMT2AALDH1A1MAPTKDM4EAPEX1
SCHEMBL22187118 0.83 APEX1 (0.51) ALDH1A1MAPTKDM4EAPEX1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-4076916-B1 WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-06-12 EP claimed
EP-4121801-B1 INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX ALCON INC (CH) 2024-04-17 EP claimed
EP-4118134-B1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC (CH) 2024-02-28 EP claimed
US-11867874-B2 Insert materials with high oxygen permeability and high refractive index ALCON INC. (CH) 2024-01-09 US claimed
WO-2023228055-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO claimed
US-20230374306-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-23 US claimed
US-20230357478-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-09 US claimed
WO-2023209569-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
WO-2021181341-A1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC. (CH) 2021-09-16 WO claimed
US-20210181379-A1 WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2021-06-17 US claimed
US-20210132411-A1 CONTACT LENSES WITH SURFACES HAVING DIFFERENT SOFTNESS ALCON INC. (CH) 2021-05-06 US claimed
US-10962803-B2 Contact lenses with a lubricious coating thereon ALCON INC. (CH) 2021-03-30 US claimed
US-10920099-B2 Poly(meth)acrylamide-based copolymers with carboxyl-terminated pendant chains ALCON INC. (CH) 2021-02-16 US claimed
EP-3746820-A1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON Alcon Inc. (CH) 2020-12-09 EP claimed
EP-3655446-A1 POLY(METH)ACRYLAMIDE-BASED COPOLYMERS WITH CARBOXYL-TERMINATED PENDANT CHAINS ALCON INC. (CH) 2020-05-27 EP claimed
US-20190235277-A1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON ALCON INC. (CH) 2019-08-01 US claimed
WO-2019016696-A1 POLY(METH)ACRYLAMIDE-BASED COPOLYMERS WITH CARBOXYL-TERMINATED PENDANT CHAINS NOVARTIS AG (CH) 2019-01-24 WO claimed
US-20190023935-A1 POLY(METH)ACRYLAMIDE-BASED COPOLYMERS WITH CARBOXYL-TERMINATED PENDANT CHAINS ALCON INC. (CH) 2019-01-24 US claimed