Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20657261 | 1.00 | KMT2A (0.49) | KMT2APOLBALDH1A1MEN1MAPT | |
| SCHEMBL20657255 | 0.94 | ADRA1A (0.55) | KMT2APOLBALDH1A1MEN1MAPT | |
| SCHEMBL22200049 | 0.92 | ADRA1A (0.58) | POLBADRA1APRMT1PLA2G4AAPEX1 | |
| SCHEMBL9829252 | 0.92 | ADRA1A (0.58) | POLBADRA1APRMT1PLA2G4AAPEX1 | |
| SCHEMBL28416594 | 0.92 | ADRA1A (0.58) | POLBADRA1APRMT1PLA2G4AAPEX1 | |
| SCHEMBL9829255 | 0.92 | ADRA1A (0.58) | POLBADRA1APRMT1PLA2G4AAPEX1 | |
| SCHEMBL20657235 | 0.88 | ECE1 (0.42) | KMT2APOLBALDH1A1MEN1MAPT | |
| SCHEMBL19272321 | 0.85 | CNR2 (0.46) | KMT2APOLBALDH1A1MEN1MAPT | |
| SCHEMBL21610956 | 0.85 | APEX1 (0.49) | KMT2AALDH1A1MAPTKDM4EAPEX1 | |
| SCHEMBL22187118 | 0.83 | APEX1 (0.51) | ALDH1A1MAPTKDM4EAPEX1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106822983-B | Developable embolism microsphere for treating tumor diseases by minimally invasive intervention therapy and preparation method thereof | 苏州恒瑞迦俐生生物医药科技有限公司 | 2020-09-15 | — | — | CN | disclosed |