Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829255 | 1.00 | ADRA1A (0.58) | ADRA1APRMT1POLBEPHX2PLA2G2A | |
| SCHEMBL28416594 | 1.00 | ADRA1A (0.58) | ADRA1APRMT1POLBEPHX2PLA2G2A | |
| SCHEMBL9829252 | 1.00 | ADRA1A (0.58) | ADRA1APRMT1POLBEPHX2PLA2G2A | |
| SCHEMBL20657255 | 0.98 | ADRA1A (0.55) | ADRA1APRMT1POLBEPHX2PLA2G2A | |
| SCHEMBL20657261 | 0.92 | KMT2A (0.49) | ADRA1APRMT1POLBEPHX2PLA2G4A | |
| SCHEMBL28459307 | 0.92 | KMT2A (0.49) | ADRA1APRMT1POLBEPHX2PLA2G4A | |
| SCHEMBL22187118 | 0.88 | APEX1 (0.51) | MAPK1APEX1 | |
| SCHEMBL20657235 | 0.84 | ECE1 (0.42) | ADRA1APRMT1POLBPLA2G2AAPEX1 | |
| SCHEMBL25146397 | 0.84 | ADRA1A (0.61) | ADRA1APRMT1POLBEPHX2PLA2G2A | |
| SCHEMBL16579816 | 0.84 | ADRA1A (0.61) | ADRA1APRMT1POLBEPHX2PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3677589-A1 | IMPROVED METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-07-08 | — | — | EP | disclosed |