SCHEMBL20657255

SCHEMBL20657255

CC=CC(=O)NCCCCC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 0.55
PRMT1 Q99873 1/20 0.53
POLB P06746 2/20 0.49
EPHX2 P34913 10/20 0.46
PLA2G2A P14555 1/20 0.46
APEX1 P27695 1/20 0.46
MAPK1 P28482 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
CACNA1B Q00975 1/20 0.44
APBA1 Q02410 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9829252 0.98 ADRA1A (0.58) ADRA1APRMT1POLBEPHX2PLA2G2A
SCHEMBL28416594 0.98 ADRA1A (0.58) ADRA1APRMT1POLBEPHX2PLA2G2A
SCHEMBL22200049 0.98 ADRA1A (0.58) ADRA1APRMT1POLBEPHX2PLA2G2A
SCHEMBL9829255 0.98 ADRA1A (0.58) ADRA1APRMT1POLBEPHX2PLA2G2A
SCHEMBL28459307 0.94 KMT2A (0.49) ADRA1APRMT1POLBEPHX2APEX1
SCHEMBL20657261 0.94 KMT2A (0.49) ADRA1APRMT1POLBEPHX2APEX1
SCHEMBL20657235 0.86 ECE1 (0.42) ADRA1APRMT1POLBPLA2G2AAPEX1
SCHEMBL22187118 0.86 APEX1 (0.51) APEX1MAPK1KDM4EALDH1A1MAPT
SCHEMBL21610956 0.83 APEX1 (0.49) APEX1MAPK1KDM4EALDH1A1MAPT
SCHEMBL25146459 0.83 ADRA1A (0.58) ADRA1APRMT1POLBEPHX2PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-4076916-B1 WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-06-12 EP claimed
US-11999908-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-06-04 US claimed
EP-4369081-A2 METHOD FOR PRODUCING AN OPHTHALMIC PRODUCT Alcon Inc. (CH) 2024-05-15 EP claimed
EP-4121801-B1 INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX ALCON INC (CH) 2024-04-17 EP claimed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
EP-4118134-B1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC (CH) 2024-02-28 EP claimed
US-11867874-B2 Insert materials with high oxygen permeability and high refractive index ALCON INC. (CH) 2024-01-09 US claimed
WO-2023228055-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO claimed
US-20230374306-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-23 US claimed
WO-2021181307-A1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC. (CH) 2021-09-16 WO claimed
US-20210181379-A1 WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2021-06-17 US claimed
US-20210132411-A1 CONTACT LENSES WITH SURFACES HAVING DIFFERENT SOFTNESS ALCON INC. (CH) 2021-05-06 US claimed
US-10962803-B2 Contact lenses with a lubricious coating thereon ALCON INC. (CH) 2021-03-30 US claimed
US-10920099-B2 Poly(meth)acrylamide-based copolymers with carboxyl-terminated pendant chains ALCON INC. (CH) 2021-02-16 US claimed
EP-3746820-A1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON Alcon Inc. (CH) 2020-12-09 EP claimed
EP-3655446-A1 POLY(METH)ACRYLAMIDE-BASED COPOLYMERS WITH CARBOXYL-TERMINATED PENDANT CHAINS ALCON INC. (CH) 2020-05-27 EP claimed
US-20190235277-A1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON ALCON INC. (CH) 2019-08-01 US claimed
US-20190023935-A1 POLY(METH)ACRYLAMIDE-BASED COPOLYMERS WITH CARBOXYL-TERMINATED PENDANT CHAINS ALCON INC. (CH) 2019-01-24 US claimed
WO-2019016696-A1 POLY(METH)ACRYLAMIDE-BASED COPOLYMERS WITH CARBOXYL-TERMINATED PENDANT CHAINS NOVARTIS AG (CH) 2019-01-24 WO claimed