SCHEMBL2066940

SCHEMBL2066940

Fc1ccccc1C(c1ccccc1F)c1ccccc1F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.45
TDO2 P48775 2/20 0.45
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
GAA P10253 2/20 0.42
MGAM O43451 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
ACHE P22303 1/20 0.41
CYP3A4 P08684 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2C9 P11712 1/20 0.39
NFE2L2 Q16236 1/20 0.39
CNR2 P34972 1/20 0.38
OPRM1 P35372 1/20 0.36
OPRD1 P41143 1/20 0.36
OPRK1 P41145 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17221914 0.85 GAA (0.42) IDO1TDO2CES2CES1GAA
SCHEMBL41457 0.84 IDO1 (0.53) IDO1TDO2CES2CES1GAA
SCHEMBL11602791 0.79 CES2 (0.54) IDO1TDO2CES2CES1GAA
SCHEMBL9808164 0.79 IDO1 (0.43) IDO1TDO2CES2CES1GAA
SCHEMBL29768740 0.79 IDO1 (0.43) IDO1TDO2CES2CES1GAA
SCHEMBL1999868 0.79 IDO1 (0.43) IDO1TDO2CES2CES1GAA
SCHEMBL15903486 0.77 ACHE (0.43) IDO1TDO2CES2CES1ACHE
SCHEMBL12568801 0.77 IDO1 (0.47) IDO1TDO2CES2CES1GAA
SCHEMBL3406218 0.77 IDO1 (0.42) IDO1TDO2CES2CES1GAA
SCHEMBL4428258 0.77 ALDH1A1 (0.46) IDO1TDO2CES2CES1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707014-B1 PROCESS FOR PRODUCING AROMATIC VINYL COMPOUND COPOLYMER IDEMITSU KOSAN CO (JP) 1999-02-17 EP claimed
US-5747613-A Process for producing aromatic vinyl compound-based copolymer IDEMITSU KOSAN CO., LTD. (JP) 1998-05-05 US claimed
EP-3848399-B1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO (JP) 2024-07-10 EP disclosed
US-11795188-B2 Transition metal compound and method for producing olefin polymer IDEMITSU KOSAN CO., LTD. (JP) 2023-10-24 US disclosed
EP-3130612-B1 PRODUCTION METHOD FOR OLEFIN-BASED POLYMER, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN-BASED POLYMER IDEMITSU KOSAN CO (JP) 2023-09-06 EP disclosed
EP-3848399-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER Idemitsu Kosan Co., Ltd. (JP) 2021-07-14 EP disclosed
US-20210198300-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO.,LTD. (JP) 2021-07-01 US disclosed
EP-3130613-B1 PRODUCTION METHOD FOR OLEFIN-BASED POLYMER, AND OLEFIN POLYMERIZATION CATALYST IDEMITSU KOSAN CO (JP) 2021-03-10 EP disclosed
US-10246531-B2 Production method for olefin-based polymer, olefin polymerization catalyst, and olefin-based polymer IDEMITSU KOSAN CO., LTD. (JP) 2019-04-02 US disclosed
US-10150825-B2 Production method for olefin-based polymer, and olefin polymerization catalyst IDEMITSU KOSAN CO., LTD. (JP) 2018-12-11 US disclosed
EP-3130612-A1 PRODUCTION METHOD FOR OLEFIN-BASED POLYMER, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN-BASED POLYMER Idemitsu Kosan Co., Ltd (JP) 2017-02-15 EP disclosed
EP-1498432-A1 PROCESS FOR PRODUCING HIGHLY FLOWABLE PROPYLENE POLYMER AND HIGHLY FLOWABLE PROPYLENE POLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 2005-01-19 EP disclosed
EP-1477499-A1 HIGHLY FLOWABLE 1-BUTENE POLYMER AND PROCESS FOR PRODUCING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-11-17 EP disclosed
US-20030203810-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-30 US disclosed
US-6586356-B2 Coordination catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-01 US disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
EP-0707014-B1 PROCESS FOR PRODUCING AROMATIC VINYL COMPOUND COPOLYMER IDEMITSU KOSAN CO (JP) 1999-02-17 EP disclosed
US-5747613-A Process for producing aromatic vinyl compound-based copolymer IDEMITSU KOSAN CO., LTD. (JP) 1998-05-05 US disclosed
EP-0707014-A1 PROCESS FOR PRODUCING AROMATIC VINYL COMPOUND COPOLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 1996-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210198300-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER H1-0, C9, C5 IDO1 1810/4885TDO2 3438/4885CES2 2388/4885
US-11795188-B2 Transition metal compound and method for producing olefin polymer H1-0, C9, C5 IDO1 1810/4885TDO2 3438/4885CES2 2388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.