Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 10/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622242 | 0.80 | KMT2A (0.37) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL10442701 | 0.78 | KMT2A (0.39) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10989262 | 0.76 | PTGDR2 (0.41) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2065922 | 0.74 | KDM4E (0.51) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2067285 | 0.74 | TP53 (0.49) | KDM4EACLYPTGDR2CYP2A6CSNK2A1 | |
| SCHEMBL16192822 | 0.73 | PTGDR2 (0.62) | KDM4ETDP1KMT2AACLYPTGDR2 | |
| SCHEMBL2065920 | 0.71 | ALDH1A1 (0.34) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11037554 | 0.71 | CYP2A6 (0.44) | KDM4EALDH1A1CYP1A2HPGDMEN1 | |
| SCHEMBL5486043 | 0.68 | CYP2A6 (0.46) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL2140618 | 0.67 | CYP2A6 (0.50) | ALDH1A1CYP1A2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507551-B2 | Antimicrobial therapy for bacterial infections | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-08-13 | — | — | US | claimed |
| US-20090042976-A1 | Antimicrobial therapy for bacterial infections | THE REGENTS OF THE UNIVERSITY OF CALIFORNIS (US) | 2009-02-12 | — | — | US | claimed |
| US-8778913-B2 | Antimicrobial compositions for treating microbial infections | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-07-15 | — | — | US | disclosed |
| US-20140154302-A1 | ANTIMICROBIAL COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | THE UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (US) | 2014-06-05 | — | — | US | disclosed |
| US-8507551-B2 | Antimicrobial therapy for bacterial infections | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-08-13 | — | — | US | disclosed |
| US-8148352-B2 | Antimicrobial therapy for bacterial infections | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-04-03 | — | — | US | disclosed |
| US-20090306021-A1 | ANTIMICROBIAL THERAPY FOR BACTERIAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090042976-A1 | Antimicrobial therapy for bacterial infections | THE REGENTS OF THE UNIVERSITY OF CALIFORNIS (US) | 2009-02-12 | — | — | US | disclosed |
| EP-2020857-A2 | ANTIMICROBIAL THERAPY FOR BACTERIAL INFECTIONS | The Regents of the University of California (US) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007133712-A2 | ANTIMICROBIAL THERAPY FOR BACTERIAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306021-A1 | ANTIMICROBIAL THERAPY FOR BACTERIAL INFECTIONS | SERPINB1, CUTA, SRRT | KDM4E 4404/4885ALDH1A1 3696/4885CYP1A2 4649/4885 |
| US-20140154302-A1 | ANTIMICROBIAL COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | MPO, CUTA, STING1 | KDM4E 4496/4885ALDH1A1 4017/4885CYP1A2 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.