SCHEMBL20679835

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8862300	0.91	KMT2A (0.68)	KMT2AKDM4EMAPTALDH1A1HPGD
	SCHEMBL9166162	0.82	TDP1 (0.72)	KMT2AMAPTALDH1A1HPGDMEN1
	SCHEMBL14166129	0.82	KMT2A (0.62)	KMT2AKDM4EMAPTALDH1A1HPGD
	SCHEMBL754900	0.81	KMT2A (0.76)	KMT2AKDM4EMAPTALDH1A1HPGD
	SCHEMBL20679817	0.79	KMT2A (0.69)	KMT2AKDM4EMAPTALDH1A1HPGD
	SCHEMBL20679874	0.79	NPC1 (0.55)	KMT2AMAPTALDH1A1MEN1CA12
	SCHEMBL9696689	0.79	TDP1 (0.72)	KMT2AMAPTALDH1A1HPGDMEN1
	SCHEMBL20679883	0.77	KMT2A (0.59)	KMT2AKDM4EMAPTALDH1A1HPGD
	SCHEMBL5736896	0.77	KMT2A (0.76)	KMT2AKDM4EMAPTALDH1A1HPGD
	SCHEMBL18736538	0.77	TDP1 (0.64)	KMT2AKDM4EMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.