SCHEMBL754900

SCHEMBL754900

O=C(OCc1ccc(Br)cc1)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.76
TDP1 Q9NUW8 3/20 0.76
SLC6A2 P23975 1/20 0.76
SLC6A3 Q01959 1/20 0.76
KDM4E B2RXH2 3/20 0.71
HPGD P15428 6/20 0.65
MAPT P10636 4/20 0.65
ALDH1A1 P00352 4/20 0.65
LMNA P02545 2/20 0.64
NPC1 O15118 3/20 0.63
RAB9A P51151 3/20 0.63
MEN1 O00255 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
TSHR P16473 1/20 0.57
MMP1 P03956 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.53
FABP7 O15540 1/20 0.52
FABP5 Q01469 1/20 0.52
TP53 P04637 1/20 0.52
CYP1A2 P05177 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5736896 0.93 KMT2A (0.76) KMT2ATDP1SLC6A2SLC6A3KDM4E
SCHEMBL5085718 0.91 KMT2A (0.92) KMT2ATDP1SLC6A2SLC6A3KDM4E
Benzyl Benzoate SCHEMBL8010992 0.87 KMT2A (1.00) KMT2ATDP1SLC6A2SLC6A3KDM4E
Benzyl Benzoate SCHEMBL3038 0.87 KMT2A (1.00) KMT2ATDP1SLC6A2SLC6A3KDM4E
Benzyl Benzoate SCHEMBL901058 0.87 KMT2A (1.00) KMT2ATDP1SLC6A2SLC6A3KDM4E
SCHEMBL6759824 0.86 KMT2A (0.56) KMT2ATDP1SLC6A2SLC6A3KDM4E
SCHEMBL4650584 0.86 KMT2A (0.76) KMT2ATDP1SLC6A2SLC6A3KDM4E
SCHEMBL2238592 0.85 LMNA (0.86) KMT2ATDP1SLC6A2SLC6A3HPGD
Benzyl Benzoate SCHEMBL29007153 0.85 KMT2A (0.96) KMT2ATDP1SLC6A2SLC6A3KDM4E
Benzyl Benzoate SCHEMBL29144647 0.85 KMT2A (0.96) KMT2ATDP1SLC6A2SLC6A3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115335043-B PGDH inhibitors and methods of making and using the same 迈欧伏特治疗公司 2025-03-28 CN disclosed
EP-2902385-B1 DEPROTECTION METHOD FOR TETRAZOLE COMPOUND API CORP (JP) 2019-01-09 EP disclosed
EP-2891650-B1 METHOD FOR PRODUCING BIARYL COMPOUND API CORP (JP) 2018-08-01 EP disclosed
US-9624181-B2 Method for producing biaryl compound API CORPORATION (JP) 2017-04-18 US disclosed
US-9624181-B2 Method for producing biaryl compound API CORPORATION (JP) 2017-04-18 US disclosed
US-9624181-B2 Method for producing biaryl compound API CORPORATION (JP) 2017-04-18 US disclosed
US-9527821-B2 Deprotection method for tetrazole compound API CORPORATION (JP) 2016-12-27 US disclosed
US-9527821-B2 Deprotection method for tetrazole compound API CORPORATION (JP) 2016-12-27 US disclosed
US-9527821-B2 Deprotection method for tetrazole compound API CORPORATION (JP) 2016-12-27 US disclosed
US-20150239854-A1 DEPROTECTION METHOD FOR TETRAZOLE COMPOUND API CORPORATION (JP) 2015-08-27 US disclosed
US-7998956-B2 Benzoxazines and related nitrogen-containing heterobicyclic compounds useful as mineralocorticoid receptor modulating agents MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-08-16 US disclosed
CN-101379048-A Benzo  oxazines and related nitrogen-containing heterobicyclic compounds useful as mineralocorticoid receptor modulating agents MITSUBISHI TANABE PHARMA CORP (JP) 2009-03-04 CN disclosed
US-20090023716-A1 Benzoxazines and Related Nitrogen-Containing Heterobicyclic Compounds Useful as Mineralocorticoid Receptor Modulating Agents MITSUBISHI TANABE PHARMA CORPORATION (JP) 2009-01-22 US disclosed
EP-1984345-A1 BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS Mitsubishi Tanabe Pharma Corporation (JP) 2008-10-29 EP disclosed
WO-2007089034-A1 BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-08-09 WO disclosed
US-5998346-A Non-phosphate machine dishwashing compositions containing copolymers of alkylene oxide adducts of allyl alcohol and acrylic acid BASF CORPORATION (US) 1999-12-07 US disclosed
US-5759978-A REDUCING SPOTTING AND FILMING OF DISHWARE BASF CORPORATION (US) 1998-06-02 US disclosed
US-5750483-A MACHINE DISHWASHING COMPOSITION BASF CORPORATION (US) 1998-05-12 US disclosed
EP-0778340-A2 Improved non-phosphate machine dishwashing compositions containing copolymers of alkylene oxide adducts of allyl alcohol and acrylic acid BASF CORPORATION (US) 1997-06-11 EP disclosed
EP-0778339-A2 Improved non-phosphate machine dishwashing compositions containing polycarboxylate polymers and nonionic graft copolymers of vinyl acetate and polyalkylene oxide BASF CORPORATION (US) 1997-06-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150239854-A1 DEPROTECTION METHOD FOR TETRAZOLE COMPOUND AGTR2, AGTR1, REN KMT2A 1824/4885TDP1 4611/4885SLC6A2 235/4885
US-20090023716-A1 Benzoxazines and Related Nitrogen-Containing Heterobicyclic Compounds Useful as Mineralocorticoid Receptor Modulating Agents NR3C2, MC2R, NR3C1 KMT2A 2504/4885TDP1 4813/4885SLC6A2 970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.