Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22894052 | 0.83 | LPAR1 (0.42) | POLBKMT2AMEN1MAPK1F2 | |
| SCHEMBL20482186 | 0.81 | RAB9A (0.43) | POLBKMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL23117635 | 0.81 | PYCR1 (0.54) | POLBKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL20528670 | 0.80 | HPGD (0.37) | POLBKMT2AMEN1MAPK1F2 | |
| SCHEMBL20505225 | 0.77 | HPGD (0.43) | POLBKMT2AMEN1F2SMN1; SMN2 | |
| SCHEMBL5790489 | 0.76 | POLB (0.69) | POLBKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL10206928 | 0.74 | HDAC1 (0.40) | POLBKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20551227 | 0.72 | POLB (0.41) | POLBF2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL20551228 | 0.72 | POLB (0.41) | POLBF2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23117637 | 0.72 | PLOD2 (0.49) | POLBKMT2ASMN1; SMN2HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110959005-B | Preparation of substituted 3-aryl-5-trifluoromethyl-1, 2, 4-oxadiazoles | 巴斯夫欧洲公司 | 2024-01-19 | — | — | CN | disclosed |
| US-20200231556-A1 | PREPARATION OF SUBSTITUTED 3-ARYL-5-TRIFLUOROMETHYL-1,2,4-OXADIAZOLES | BASF SE (DE) | 2020-07-23 | — | — | US | disclosed |
| EP-3658543-A1 | PREPARATION OF SUBSTITUTED 3-ARYL-5-TRIFLUOROMETHYL-1,2,4-OXADIAZOLES | BASF SE (DE) | 2020-06-03 | — | — | EP | disclosed |
| CN-110959005-A | Preparation of substituted 3-aryl-5-trifluoromethyl-1, 2, 4-oxadiazoles | 巴斯夫欧洲公司 | 2020-04-03 | — | — | CN | disclosed |
| WO-2019020501-A1 | PREPARATION OF SUBSTITUTED 3-ARYL-5-TRIFLUOROMETHYL-1,2,4-OXADIAZOLES | BASF SE (DE) | 2019-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231556-A1 | PREPARATION OF SUBSTITUTED 3-ARYL-5-TRIFLUOROMETHYL-1,2,4-OXADIAZOLES | CYP4F3, CYP51A1, CYP4B1 | POLB 4073/4885KMT2A 2019/4885MEN1 3633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.