Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790489 | 0.81 | POLB (0.69) | POLBKMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL20680717 | 0.81 | POLB (0.45) | POLBKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31725230 | 0.79 | PYCR1 (0.59) | PYCR1POLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2238302 | 0.79 | ALDH1A1 (0.69) | PYCR1POLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL23117637 | 0.78 | PLOD2 (0.49) | POLBKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL13450089 | 0.76 | POLB (0.63) | POLBKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3154235 | 0.76 | POLB (0.63) | POLBKMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL26522756 | 0.76 | POLB (0.49) | PYCR1POLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24636855 | 0.75 | POLB (0.66) | POLBKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL26522945 | 0.75 | KMT2A (0.50) | POLBKMT2ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3619207-B1 | SUBSTITUTED 5-(HALOALKYL)-5-HYDROXY-ISOXAZOLINES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2021-06-23 | — | — | EP | disclosed |
| US-20210084900-A1 | Substituted 5-(haloalkyl)-5-hydroxy-isoxazoles for Combating Phytopathogenic Fungi | BASF SE (DE) | 2021-03-25 | — | — | US | disclosed |
| CN-110621669-A | Substituted 5-haloalkyl-5-hydroxyisoxazoles for controlling phytopathogenic fungi | 巴斯夫欧洲公司 | 2019-12-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210084900-A1 | Substituted 5-(haloalkyl)-5-hydroxy-isoxazoles for Combating Phytopathogenic Fungi | HAX1, HAO1, HAO2 | PYCR1 2014/4885POLB 3943/4885KMT2A 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.