Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20686294 | 0.85 | MEN1 (0.35) | MEN1KMT2AUSP2PABPC1TSHR | |
| SCHEMBL20686222 | 0.81 | TGFBR1 (0.36) | MEN1KMT2AUSP2PABPC1TGFBR1 | |
| SCHEMBL17633302 | 0.77 | JAK2 (0.40) | MEN1KMT2AJAK2 | |
| SCHEMBL17051052 | 0.77 | TRPV1 (0.41) | MEN1KMT2ANPSR1 | |
| SCHEMBL18557597 | 0.76 | MEN1 (0.43) | MEN1KMT2ANPSR1NNMT | |
| SCHEMBL18327670 | 0.75 | IDO1 (0.41) | MEN1KMT2AUSP2PABPC1NPSR1 | |
| SCHEMBL16114660 | 0.75 | RECQL (0.37) | MEN1KMT2AUSP2PABPC1NPSR1 | |
| SCHEMBL20686251 | 0.74 | LMNA (0.38) | MEN1KMT2ACTSA | |
| SCHEMBL17629783 | 0.74 | F11 (0.38) | MEN1KMT2AUSP2PABPC1NPSR1 | |
| SCHEMBL23332599 | 0.73 | NNMT (0.43) | MEN1KMT2APABPC1TSHRNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197872-B1 | (2H)-2-OXOPYRIDINES AS FAKTOR XIA-INHIBITORS FOR TREATING THROMBOTIC DISEASES | Bayer Pharma AG (DE) | 2019-01-30 | — | — | EP | disclosed |