Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20686264 | 0.85 | MEN1 (0.36) | MEN1KMT2AUSP2PABPC1TGFBR1 | |
| SCHEMBL20686222 | 0.80 | TGFBR1 (0.36) | MEN1KMT2AUSP2PABPC1TGFBR1 | |
| SCHEMBL17633224 | 0.77 | SRC (0.42) | MAPT | |
| SCHEMBL17051052 | 0.76 | TRPV1 (0.41) | MEN1KMT2ANPSR1MAPTALOX15 | |
| SCHEMBL16114660 | 0.74 | RECQL (0.37) | MEN1KMT2AUSP2PABPC1RECQL | |
| SCHEMBL17629783 | 0.73 | F11 (0.38) | MEN1KMT2AUSP2PABPC1RECQL | |
| SCHEMBL31449583 | 0.73 | OXTR (0.41) | MEN1KMT2AL3MBTL1TSHRNPC1 | |
| SCHEMBL20686251 | 0.70 | LMNA (0.38) | MEN1KMT2AP2RX3P2RX2NPC1 | |
| SCHEMBL21737273 | 0.70 | P2RX3 (0.40) | MEN1KMT2APABPC1P2RX3P2RX2 | |
| SCHEMBL16115593 | 0.69 | F11 (0.40) | MAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197872-B1 | (2H)-2-OXOPYRIDINES AS FAKTOR XIA-INHIBITORS FOR TREATING THROMBOTIC DISEASES | Bayer Pharma AG (DE) | 2019-01-30 | — | — | EP | disclosed |