Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 5/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | ALAD | P13716 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20695443 | 0.81 | HTR3E (0.38) | MGLLBRD4USP2ALDH1A1CYP3A4 | |
| SCHEMBL20695210 | 0.80 | MAPK1 (0.50) | L3MBTL1USP2ALDH1A1CYP3A4HPGD | |
| SCHEMBL20695092 | 0.80 | RAB9A (0.43) | HDAC6ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL20695340 | 0.80 | BRD4 (0.50) | MGLLBRD4USP2ALDH1A1CYP3A4 | |
| SCHEMBL20695447 | 0.78 | MGLL (0.39) | MGLLSCD5BRD4USP2ALDH1A1 | |
| SCHEMBL20695190 | 0.76 | GHSR (0.43) | MGLLBRD4USP2ALDH1A1CYP3A4 | |
| SCHEMBL20695299 | 0.76 | GHSR (0.44) | MGLLBRD4USP2ALDH1A1HPGD | |
| SCHEMBL20695496 | 0.76 | MGLL (0.39) | HDAC6MGLLBRD4PDE4B | |
| SCHEMBL20695396 | 0.76 | PDCD1LG2 (0.37) | MGLLBRD4USP2ALDH1A1CYP3A4 | |
| SCHEMBL20695172 | 0.75 | HRH4 (0.52) | HDAC6L3MBTL1ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10610520-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-04-07 | — | — | US | disclosed |
| US-20190125728-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-05-02 | — | — | US | disclosed |
| US-20190125728-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-05-02 | — | — | US | disclosed |
| EP-3438109-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2019-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190125728-A1 | HETEROCYCLIC COMPOUND | MAG, HTT, ACHE | HDAC6 91/4885MMP12 421/4885USP30 4327/4885 |
| US-10610520-B2 | Heterocyclic compound | MAG, HTT, ACHE | HDAC6 91/4885MMP12 421/4885USP30 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.