Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 6/20 | 0.40 |
| ▸ | NPY1R | P25929 | 4/20 | 0.40 |
| ▸ | NPY2R | P49146 | 3/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780232 | 0.93 | NPY4R (0.40) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| SCHEMBL7780233 | 0.93 | NPY4R (0.40) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| Arginine SCHEMBL20702218 | 0.92 | NPY4R (0.40) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| Arginine SCHEMBL19283975 | 0.86 | FNTA (0.41) | NPY4RNPY1REGLN2 | |
| Arginine SCHEMBL27381977 | 0.83 | ALDH1A1 (0.43) | ANPEPRNPEPDNPEPL3MBTL1GAA | |
| SCHEMBL27779867 | 0.82 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RGAA | |
| SCHEMBL1551972 | 0.81 | SLC7A5 (0.47) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL1231526 | 0.81 | SLC7A5 (0.47) | NPY4RNPY1RNPY2RNPY5R | |
| Lactic Acid SCHEMBL12076709 | 0.80 | NOD1 (0.40) | NPY4RNPY1RNPY2RNPY5R | |
| Lactic Acid SCHEMBL12076711 | 0.80 | NOD1 (0.40) | NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190038532-A1 | METHOD FOR TREATING HAIR | KAO CORPORATION (JP) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190038532-A1 | METHOD FOR TREATING HAIR | TYR, POLR1C, CA7 | NPY4R 3778/4885NPY1R 3027/4885NPY2R 2891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.