Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834499 | 0.84 | APP (0.53) | APPALDH1A1KDM4ECHRM2CHRM1 | |
| SCHEMBL18980591 | 0.81 | APP (0.41) | APPALDH1A1KDM4ECHRM2CHRM1 | |
| SCHEMBL18980593 | 0.81 | APP (0.41) | APPALDH1A1KDM4ECHRM2CHRM1 | |
| SCHEMBL19010037 | 0.80 | LMNA (0.41) | TSHRKDM4ECHRM2CHRM1GRM5 | |
| SCHEMBL8706112 | 0.80 | CYP1A2 (0.44) | APPALDH1A1CYP3A4KDM4ECA12 | |
| SCHEMBL18980647 | 0.79 | RARB (0.38) | APPTSHRSMN1; SMN2KCNH2MAPT | |
| SCHEMBL18980910 | 0.76 | KIF11 (0.35) | SMN1; SMN2KCNH2EGLN1 | |
| SCHEMBL6201292 | 0.74 | APP (0.55) | APPALDH1A1CYP3A4KDM4ECHRM2 | |
| SCHEMBL23005133 | 0.73 | CHRM2 (0.37) | APPALDH1A1TP53CYP3A4ALOX15 | |
| 1-Allyloxy-4-Methoxybenzene SCHEMBL2843640 | 0.73 | ALDH1A1 (0.57) | ALDH1A1TP53CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168097-B2 | Photochemical methods of making cyclobutane boronates and related compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2021-11-09 | — | — | US | disclosed |
| US-11168097-B2 | Photochemical methods of making cyclobutane boronates and related compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200223870-A1 | PHOTOCHEMICAL METHODS OF MAKING CYCLOBUTANE BORONATES AND RELATED COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-07-16 | — | — | US | disclosed |
| US-20200223870-A1 | PHOTOCHEMICAL METHODS OF MAKING CYCLOBUTANE BORONATES AND RELATED COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-07-16 | — | — | US | disclosed |
| US-10618917-B2 | Photochemical methods of making cyclobutane boronates and related compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-04-14 | — | — | US | disclosed |
| US-20190040085-A1 | PHOTOCHEMICAL METHODS OF MAKING CYCLOBUTANE BORONATES AND RELATED COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-02-07 | — | — | US | disclosed |
| US-20190040085-A1 | PHOTOCHEMICAL METHODS OF MAKING CYCLOBUTANE BORONATES AND RELATED COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168097-B2 | Photochemical methods of making cyclobutane boronates and related compounds | BLVRB, CYP11B2, CYP11B1 | APP 1244/4885ALDH1A1 1603/4885TP53 3277/4885 |
| US-20190040085-A1 | PHOTOCHEMICAL METHODS OF MAKING CYCLOBUTANE BORONATES AND RELATED COMPOUNDS | BLVRB, CYP11B1, CYP11B2 | APP 1241/4885ALDH1A1 1582/4885TP53 3250/4885 |
| US-10618917-B2 | Photochemical methods of making cyclobutane boronates and related compounds | BLVRB, CYP11B2, CYP11B1 | APP 1244/4885ALDH1A1 1603/4885TP53 3277/4885 |
| US-20200223870-A1 | PHOTOCHEMICAL METHODS OF MAKING CYCLOBUTANE BORONATES AND RELATED COMPOUNDS | BLVRB, CYP11B2, CYP11B1 | APP 1244/4885ALDH1A1 1603/4885TP53 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.