Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902268 | 1.00 | DRD2 (0.44) | DRD2DRD3LMNAMAPTKDM4E | |
| SCHEMBL7458987 | 1.00 | DRD2 (0.44) | DRD2DRD3LMNAMAPTKDM4E | |
| SCHEMBL19035629 | 0.91 | LMNA (0.52) | DRD2DRD3LMNAMAPTKDM4E | |
| SCHEMBL19035590 | 0.84 | DPP4 (0.50) | DRD2DRD3LMNAMAPTKDM4E | |
| SCHEMBL7469756 | 0.83 | KDM4E (0.47) | DRD2DRD3LMNAMAPTKDM4E | |
| SCHEMBL7897457 | 0.83 | KDM4E (0.47) | DRD2DRD3LMNAMAPTKDM4E | |
| SCHEMBL2070684 | 0.81 | KDM4E (0.56) | LMNAMAPTKDM4ECYP2C19ALDH1A1 | |
| SCHEMBL9203045 | 0.81 | HTR1A (0.56) | HTR1A | |
| SCHEMBL3879984 | 0.81 | HTR1A (0.56) | HTR1A | |
| SCHEMBL9201106 | 0.81 | HTR1A (0.56) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191130-B1 | HYPOTENSIVE AGENTS; THERAPY FOR SEXUAL DISORDERS; CENTRAL NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | PIERRE FABRE MEDICAMENT (FR) | 2001-02-20 | — | — | US | disclosed |