Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942724 | 0.86 | CYP2C19 (0.43) | CYP2C19POLBALOX5CES2CES1 | |
| SCHEMBL27347276 | 0.84 | ALOX5 (0.42) | CYP2C19POLBALOX5CES2CES1 | |
| SCHEMBL6464486 | 0.84 | ALOX5 (0.50) | CYP2C19POLBALOX5CES2CES1 | |
| SCHEMBL10210730 | 0.84 | ALOX5 (0.50) | CYP2C19POLBALOX5CES2CES1 | |
| SCHEMBL4215659 | 0.83 | GLS (0.48) | CYP2C19POLBALOX5CES2CES1 | |
| SCHEMBL14782240 | 0.83 | ALOX5 (0.40) | CYP2C19POLBALOX5CES2CES1 | |
| SCHEMBL28170178 | 0.83 | HTT (0.45) | CYP2C19POLBALOX5CES2CES1 | |
| SCHEMBL30688429 | 0.81 | POLB (0.49) | CYP2C19POLBALOX5CES2CES1 | |
| SCHEMBL3308161 | 0.81 | ALOX5 (0.37) | CYP2C19POLBALOX5CES2CES1 | |
| SCHEMBL11635124 | 0.81 | CYP2C19 (0.46) | CYP2C19POLBALOX5CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425528-A1 | AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS | PROTOMER TECH INC (US) | 2024-12-26 | — | — | US | disclosed |
| US-12139502-B2 | Aromatic boron-containing compounds and related insulin analogs | PROTOMER TECHNOLOGIES INC. (US) | 2024-11-12 | — | — | US | disclosed |
| CN-115894434-B | Preparation method of 4-piperazinyl benzothiophene hydrochloride | 山东厚德精诚药业有限公司 | 2024-10-08 | — | — | CN | disclosed |
| US-11828741-B2 | Sensor that detects an analyte in the presence of an interfering stimulus | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-11-28 | — | — | US | disclosed |
| US-20230374045-A1 | AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS | PROTOMER TECHNOLOGIES INC. | 2023-11-23 | — | — | US | disclosed |
| CN-115894434-A | Preparation method of 4-piperazinyl benzothiophene hydrochloride | 山东厚德精诚药业有限公司 | 2023-04-04 | — | — | CN | disclosed |
| EP-4041249-A1 | COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES | The Scripps Research Institute (US) | 2022-08-17 | — | — | EP | disclosed |
| WO-2022170108-A1 | PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF IN PREVENTION OF RADIATION INJURY | AILERON THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| US-20210156837-A1 | SENSOR THAT DETECTS AN ANALYTE IN THE PRESENCE OF AN INTERFERING STIMULUS | THE JOHNS HOPKINS UNIVERSITY | 2021-05-27 | — | — | US | disclosed |
| US-10550143-B2 | C,O-spiro aryl glycoside compounds, preparation therefor and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-02-04 | — | — | US | disclosed |
| WO-2007144140-A1 | A PROCESS FOR THE PREPARATION OF POLY-ALFA-GLUTAMIC ACID AND DERIVATIVES THEREOF | CELL THERAPEUTICS INC. - SEDE SECONDARIA (IT) | 2007-12-21 | — | — | WO | disclosed |
| US-20070284258-A1 | Method For Silver Plating | DAIWA FINE CHEMICALS CO., LTD. (JP) | 2007-12-13 | — | — | US | disclosed |
| US-20070072833-A1 | Survivin inhibitors | ABBVIE INC. | 2007-03-29 | — | — | US | disclosed |
| WO-2004026848-A1 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPERATION AND THEIR USE AS ANTIMYCOBACTERIAL AGENTS | LUPIN LIMITED (IN) | 2004-04-01 | — | — | WO | disclosed |
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
| WO-1996040732-A1 | COMBINATORIAL NON-PEPTIDE LIBRARIES | ZYMOGENETICS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| CN-1070645-A | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORP (US) | 1993-04-07 | — | — | CN | disclosed |
| EP-0171213-A1 | Spiro-imidazolones for treatment of diabetic complications | PFIZER INC. (US) | 1986-02-12 | — | — | EP | disclosed |
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072833-A1 | Survivin inhibitors | XIAP, BIRC5, BIRC3 | CYP2C19 4850/4885POLB 532/4885ALOX5 3523/4885 |
| US-20240425528-A1 | AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS | IAPP, GPR119, INSR | CYP2C19 3889/4885POLB 3049/4885ALOX5 4261/4885 |
| US-10550143-B2 | C,O-spiro aryl glycoside compounds, preparation therefor and use thereof | SLC5A2, SLC5A1, GLP1R | CYP2C19 847/4885POLB 4766/4885ALOX5 1941/4885 |
| US-12139502-B2 | Aromatic boron-containing compounds and related insulin analogs | IAPP, GPR119, INSR | CYP2C19 3889/4885POLB 3049/4885ALOX5 4261/4885 |
| US-20230374045-A1 | AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS | IAPP, GPR119, INSR | CYP2C19 3889/4885POLB 3049/4885ALOX5 4261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.