SCHEMBL20713855

SCHEMBL20713855

CBn1cc(NC(C)C(C)C)nn1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22922372 0.69
SCHEMBL17296968 0.63
SCHEMBL22922495 0.63
SCHEMBL21017396 0.59 TRPM8 (0.36) HCAR3
SCHEMBL15354447 0.57 ESR1 (0.41) HCAR3
SCHEMBL15354462 0.57 ESR1 (0.41) HCAR3
SCHEMBL22503417 0.57
SCHEMBL24567545 0.56 ALDH1A1 (0.49)
SCHEMBL23059301 0.56 MEN1 (0.42) HCAR3
SCHEMBL23059377 0.56 MEN1 (0.42) HCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10716858-B2 Branched multi-functional macromonomers and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-07-21 US disclosed
US-20190038751-A1 BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2019-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190038751-A1 BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND USES THEREOF MSN, NEDD8, CAD HCAR3 2654/4885
US-10716858-B2 Branched multi-functional macromonomers and uses thereof MSN, NEDD8, CAD HCAR3 2654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.