Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 11/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31260595 | 0.88 | MAPT (0.35) | MAPTALDH1A1SMN1; SMN2PDK1 | |
| SCHEMBL26858 | 0.87 | HCAR3 (0.41) | HCAR3MAPTTSHRCASP6ALDH1A1 | |
| SCHEMBL3141355 | 0.83 | LMNA (0.41) | HCAR3MAPTTSHRCASP6ALDH1A1 | |
| SCHEMBL16016767 | 0.77 | ESR1 (0.42) | MAPTALDH1A1 | |
| SCHEMBL26859 | 0.76 | MAPT (0.35) | MAPTALDH1A1PDK1 | |
| SCHEMBL27469910 | 0.75 | LMNA (0.40) | HCAR3MAPTTSHRCASP6ALDH1A1 | |
| SCHEMBL3141351 | 0.74 | KMT2A (0.47) | HCAR3MAPTTSHRCASP6ALDH1A1 | |
| SCHEMBL27469909 | 0.73 | KMT2A (0.51) | HCAR3MAPTCASP6ALDH1A1SMN1; SMN2 | |
| SCHEMBL29008623 | 0.72 | KMT2A (0.47) | — | |
| SCHEMBL21319 | 0.72 | CASP6 (0.57) | HCAR3TSHRCASP6PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609107-B1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) | 2024-12-11 | — | — | EP | disclosed |
| US-20210300954-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2021-09-30 | — | — | US | disclosed |
| CN-103889999-B | Ion labeling for oligoribonucleotide synthesis | 皇家学习促进学会/麦吉尔大学 | 2021-06-01 | — | — | CN | disclosed |
| US-11014948-B2 | Ionic tags for synthesis of oligoribonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2021-05-25 | — | — | US | disclosed |
| EP-2748176-B1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) | 2019-04-17 | — | — | EP | disclosed |
| US-9920084-B2 | Ionic tags for synthesis of oligoribonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2018-03-20 | — | — | US | disclosed |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2014-09-11 | — | — | US | disclosed |
| EP-2748176-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | The Royal Institution for the Advancement of Learning / McGill University (CA) | 2014-07-02 | — | — | EP | disclosed |
| EP-2609107-A1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | The Royal Institution for the Advancement of Learning / McGill University (CA) | 2013-07-03 | — | — | EP | disclosed |
| WO-2013026142-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2013-02-28 | — | — | WO | disclosed |
| WO-2012024776-A1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11014948-B2 | Ionic tags for synthesis of oligoribonucleotides | RNGTT, OSTC, DTYMK | HCAR3 3233/4885MAPT 1176/4885TSHR 2662/4885 |
| US-20210300954-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | RNGTT, OSTC, DTYMK | HCAR3 3233/4885MAPT 1176/4885TSHR 2662/4885 |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | RNGTT, OSTC, OSGEP | HCAR3 3334/4885MAPT 1116/4885TSHR 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.