Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20910141 | 0.81 | ITGB3 (0.43) | ITGB3ITGAV | |
| SCHEMBL20724700 | 0.79 | ITGB3 (0.37) | ITGB3ITGAV | |
| SCHEMBL19677586 | 0.68 | ITGB3 (0.41) | ITGB3ITGAV | |
| SCHEMBL19708683 | 0.62 | THRB (0.57) | ITGB3ITGAV | |
| SCHEMBL19677575 | 0.60 | ITGB3 (0.61) | ITGB3ITGAV | |
| SCHEMBL19708684 | 0.60 | ITGB3 (0.55) | ITGB3ITGAV | |
| SCHEMBL19679617 | 0.60 | ALDH1A1 (0.39) | — | |
| SCHEMBL19677577 | 0.58 | THRB (0.35) | ITGB3ITGAV | |
| SCHEMBL24063119 | 0.57 | THRB (0.47) | ITGB3ITGAV | |
| SCHEMBL19677582 | 0.57 | THRB (0.34) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10201616-B2 | Non-cleavable polymer conjugated with αVβ3 integrin thyroid antagonists | NANOPHARMACEUTICALS, LLC (US) | 2019-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10201616-B2 | Non-cleavable polymer conjugated with αVβ3 integrin thyroid antagonists | CD44, THRA, TSHR | ITGB3 4/4885ITGAV 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.