Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MIF | P14174 | 6/20 | 0.51 |
| ▸ | CD74 | P04233 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805706 | 0.87 | MIF (0.62) | TP53MIFCD74MEN1KMT2A | |
| SCHEMBL20725153 | 0.81 | ALDH1A1 (0.67) | TP53MIFCD74MEN1KMT2A | |
| SCHEMBL17260661 | 0.78 | HSD17B3 (0.46) | MIFCD74KMT2AMETPOLB | |
| SCHEMBL2757855 | 0.78 | MIF (0.70) | MIFCD74NPC1POLBALDH1A1 | |
| SCHEMBL31667438 | 0.73 | MIF (0.71) | TP53MIFCD74MEN1KMT2A | |
| SCHEMBL31667732 | 0.72 | POLB (0.54) | TP53MIFCD74MEN1KMT2A | |
| SCHEMBL16296691 | 0.71 | MIF (0.49) | MIFCD74NPC1ALDH1A1KMO | |
| SCHEMBL15355911 | 0.71 | ESR1 (0.79) | — | |
| SCHEMBL18805693 | 0.71 | MIF (0.82) | MIFCD74ALDH1A1MAPTHPGD | |
| SCHEMBL34475640 | 0.71 | POLB (0.52) | TP53MIFCD74MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202343-B2 | MIF modulators | YALE UNIVERSITY (US) | 2019-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202343-B2 | MIF modulators | MIF, HMGB2, HMGB3 | TP53 1948/4885MIF 1/4885CD74 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.