Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | DPP4 | P27487 | 6/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3545787 | 0.83 | GPR183 (0.55) | GPR183NPC1RAB9ADPP4DPP7 | |
| SCHEMBL22731079 | 0.75 | GPR183 (0.48) | GPR183NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28228555 | 0.71 | SMN1; SMN2 (0.61) | NPC1RAB9ADPP4DPP7DPP8 | |
| SCHEMBL15345175 | 0.70 | FKBP1A (0.59) | SMN1; SMN2 | |
| SCHEMBL1990363 | 0.68 | NPC1 (0.69) | NPC1RAB9AEPHX2TDP1 | |
| SCHEMBL295136 | 0.68 | NPC1 (0.69) | NPC1RAB9AEPHX2TDP1 | |
| SCHEMBL31285848 | 0.68 | DPP4 (0.52) | NPC1RAB9ADPP4DPP7SMN1; SMN2 | |
| SCHEMBL3971804 | 0.67 | RAB9A (0.54) | NPC1RAB9AEPHX2 | |
| Hydrochloric Acid SCHEMBL28989899 | 0.66 | NPC1 (0.67) | NPC1RAB9AEPHX2TDP1 | |
| SCHEMBL693305 | 0.66 | NPC1 (0.67) | NPC1RAB9AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074397-B1 | A PROCESS FOR PREPARATION OF (2S, 5R)-7-OXO-N-[(2S)-PYRROLIDIN-2-YL-METHYLOXY]-6-(SULFOOXY)-1,6-DIAZABICYCLO[3.2.1]OCTANE-2-CARBOXAMIDE | WOCKHARDT LTD (IN) | 2019-02-13 | — | — | EP | disclosed |