Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.36 |
| ▸ | CTSC | P53634 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 5/20 | 0.33 |
| ▸ | CTSS | P25774 | 4/20 | 0.33 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23240582 | 0.83 | CTSL (0.36) | CTSLCTSCLRRK2CTSBCTSS | |
| SCHEMBL20733619 | 0.74 | HPGD (0.42) | — | |
| SCHEMBL20723571 | 0.72 | XDH (0.38) | — | |
| SCHEMBL20876195 | 0.70 | KDM4E (0.43) | — | |
| SCHEMBL25254280 | 0.69 | KMT2A (0.47) | CTSLANO1 | |
| SCHEMBL20241151 | 0.68 | LRRK2 (0.42) | CTSLLRRK2CTSSCTSKCNR1 | |
| SCHEMBL30166593 | 0.68 | LRRK2 (0.42) | CTSLLRRK2CTSSCTSKCNR1 | |
| SCHEMBL10279697 | 0.65 | CTSL (0.48) | CTSLCTSBCTSSCTSK | |
| SCHEMBL18163227 | 0.64 | P2RX7 (0.45) | CTSLLRRK2CTSSCTSKANO1 | |
| SCHEMBL17501818 | 0.64 | ANO1 (0.43) | CTSLLRRK2CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148600-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-05-18 | — | — | US | disclosed |
| US-20230148600-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-05-18 | — | — | US | disclosed |
| EP-3665170-B1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-09-15 | — | — | EP | disclosed |
| US-20200245624-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (SE) | 2020-08-06 | — | — | US | disclosed |
| WO-2019030357-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200245624-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | ACHE, DDT, GSTP1 | CTSL 2274/4885CTSC 284/4885LRRK2 257/4885 |
| US-20230148600-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | ACHE, DDT, GSTP1 | CTSL 1762/4885CTSC 140/4885LRRK2 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.