Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824624 | 0.84 | AHR (0.45) | MAOBMAOAPDE4DAHRKMT2A | |
| SCHEMBL25912057 | 0.81 | ALDH1A1 (0.47) | AHRTDP1 | |
| SCHEMBL20733838 | 0.77 | THRB (0.39) | MAOBMAOAAHRMAPT | |
| SCHEMBL20733817 | 0.77 | ALOX5 (0.50) | AHRKMT2AMEN1MAPTGABRP | |
| SCHEMBL25911712 | 0.77 | AHR (0.56) | AHRKMT2AMEN1TNKSMAPT | |
| SCHEMBL25911682 | 0.77 | AHR (0.49) | AHRKMT2AMEN1RAB9ATNKS | |
| SCHEMBL20175208 | 0.76 | MAOB (0.68) | MAOBMAOAPDE4DPTPRCPTPN1 | |
| SCHEMBL20175207 | 0.76 | MAOB (0.68) | MAOBMAOAPDE4DPTPRCPTPN1 | |
| SCHEMBL30789895 | 0.75 | GPR84 (0.44) | KMT2AMEN1MAPTKDM4E | |
| SCHEMBL25911498 | 0.74 | ALDH1A1 (0.49) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019031605-A1 | FUSED RING COMPOUND | 東ソー株式会社 | 2019-02-14 | — | — | WO | disclosed |