SCHEMBL20735017

SCHEMBL20735017

O=C1c2cccc3c(-c4ccc(-c5ccc6c7c(cccc57)C(=O)N(C5CCCCC5)C6=O)c5ccccc45)ccc(c23)C(=O)N1C1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
CYP1B1 Q16678 4/20 0.49
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ATM Q13315 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42
TLR9 Q9NR96 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CRHBP P24387 1/20 0.42
MAPK1 P28482 1/20 0.42
CRHR2 Q13324 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20735248 0.93 ALDH1A1 (0.49) ALDH1A1CYP1B1KDM4EHPGDHSD17B10
SCHEMBL20735085 0.91 ALDH1A1 (0.50) ALDH1A1CYP1B1KDM4EHPGDHSD17B10
SCHEMBL20735163 0.90 ALDH1A1 (0.49) ALDH1A1CYP1B1KDM4EHPGDHSD17B10
SCHEMBL20735196 0.90 ALDH1A1 (0.49) ALDH1A1CYP1B1KDM4EHPGDHSD17B10
SCHEMBL5520058 0.87 ALDH1A1 (0.57) ALDH1A1CYP1B1KDM4EHPGDMEN1
SCHEMBL4860229 0.87 CYP1B1 (0.66) ALDH1A1CYP1B1KDM4EMEN1KMT2A
SCHEMBL20735199 0.87 ALDH1A1 (0.49) ALDH1A1CYP1B1KDM4EHPGDHSD17B10
SCHEMBL7646060 0.87 KEAP1 (0.57) ALDH1A1CYP1B1KDM4EATMSMN1; SMN2
SCHEMBL10261468 0.85 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDHSD17B10ATM
SCHEMBL10260482 0.85 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDHSD17B10ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209862-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209862-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-11641754-B2 Organic light-emitting device and electronic apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-02 US disclosed
US-11641754-B2 Organic light-emitting device and electronic apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-02 US disclosed
US-10381596-B2 Organic light-emitting display apparatus with an encapsulation unit SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-13 US disclosed
US-20190051860-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-14 US disclosed
US-20190051856-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190051860-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS ALDH1A1, AOX1, ALDH1A2 ALDH1A1 1/4885CYP1B1 71/4885KDM4E 4393/4885
US-10381596-B2 Organic light-emitting display apparatus with an encapsulation unit ALDH1A1, AOX1, AMY1A ALDH1A1 1/4885CYP1B1 104/4885KDM4E 4278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.