Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10246603 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHRCNR2LMNAG6PC1 | |
| SCHEMBL2518042 | 0.84 | ALDH1A1 (0.46) | RORCALDH1A1TSHRCNR2RIPK1 | |
| SCHEMBL2015197 | 0.82 | RIPK1 (0.44) | RORCRECQLLMNARIPK1MMP1 | |
| SCHEMBL12842010 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TSHRCNR2LMNAG6PC1 | |
| SCHEMBL2073073 | 0.77 | HTT (0.50) | ALDH1A1TSHRCNR2LMNAG6PC1 | |
| SCHEMBL2050631 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNARIPK1MEN1 | |
| SCHEMBL25909666 | 0.74 | KDM4E (0.37) | ALDH1A1TSHRCNR2LMNAG6PC1 | |
| SCHEMBL9210778 | 0.74 | LMNA (0.40) | ALDH1A1TSHRCNR2LMNAMEN1 | |
| SCHEMBL21905878 | 0.73 | CYP1A2 (0.50) | ALDH1A1L3MBTL1 | |
| SCHEMBL10246599 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12011490-B2 | Dental photocurable composition excellent in operability and storage stability | SHOFU INC. (JP) | 2024-06-18 | — | — | US | disclosed |
| US-20220401312-A1 | DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN OPERABILITY AND STORAGE STABILITY | SHOFU INC. (JP) | 2022-12-22 | — | — | US | disclosed |
| EP-4062895-A1 | DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN OPERABILITY AND STORAGE STABILITY | Shofu Inc. (JP) | 2022-09-28 | — | — | EP | disclosed |
| CN-115068345-A | Dental adhesive composition having excellent storage stability | 株式会社松风 | 2022-09-20 | — | — | CN | disclosed |
| CN-115068346-A | Dental photocurable composition having excellent handling properties and storage stability | 株式会社松风 | 2022-09-20 | — | — | CN | disclosed |
| US-20220287918-A1 | DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY | SHOFU INC. (JP) | 2022-09-15 | — | — | US | disclosed |
| EP-4056163-A1 | DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY | Shofu Inc. (JP) | 2022-09-14 | — | — | EP | disclosed |
| US-7902356-B2 | Thiazolopyridinone derivates as MCH receptor antagonists | ELI LILLY AND COMPANY (US) | 2011-03-08 | — | — | US | disclosed |
| US-7902356-B2 | Thiazolopyridinone derivates as MCH receptor antagonists | ELI LILLY AND COMPANY (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1828207-B1 | THIAZOLOPYRIDINONE DERIVATES AS MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2009-10-28 | — | — | EP | disclosed |
| EP-1828207-B1 | THIAZOLOPYRIDINONE DERIVATES AS MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2009-10-28 | — | — | EP | disclosed |
| US-20090233919-A1 | THIAZOLOPYRIDINONE DERIVATES AS MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY | 2009-09-17 | — | — | US | disclosed |
| US-20090233919-A1 | THIAZOLOPYRIDINONE DERIVATES AS MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY | 2009-09-17 | — | — | US | disclosed |
| EP-1828207-A1 | THIAZOLOPYRIDINONE DERIVATES AS MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006066174-A1 | THIAZOLOPYRIDINONE DERIVATES AS MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12011490-B2 | Dental photocurable composition excellent in operability and storage stability | H1-0, CCND1, CCNT1 | RORC 3938/4885CTSS 651/4885CTSK 1695/4885 |
| US-20090233919-A1 | THIAZOLOPYRIDINONE DERIVATES AS MCH RECEPTOR ANTAGONISTS | MCHR1, MCHR2, MC1R | RORC 144/4885CTSS 4456/4885CTSK 4273/4885 |
| US-20220287918-A1 | DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY | ITGA1, ITGB1, CDH1 | RORC 3920/4885CTSS 3387/4885CTSK 4238/4885 |
| US-20220401312-A1 | DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN OPERABILITY AND STORAGE STABILITY | H1-0, CCND1, CCNT1 | RORC 3922/4885CTSS 638/4885CTSK 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.