SCHEMBL20738282

SCHEMBL20738282

Cc1cccc(SCC2CC2)c1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.45
CRBN Q96SW2 2/20 0.41
DDB1 Q16531 1/20 0.41
ACHE P22303 1/20 0.39
POLB P06746 2/20 0.39
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
PTGER1 P34995 1/20 0.37
PTGFR P43088 1/20 0.37
MAP1LC3B Q9GZQ8 1/20 0.36
MAP1LC3A Q9H492 1/20 0.36
HTR2C P28335 2/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20738281 0.77 AR (0.42) ARCRBNMAP1LC3BMAP1LC3AMAOA
SCHEMBL2665085 0.76 CRBN (0.51) ARCRBNNPC1RAB9AALDH1A1
SCHEMBL2665515 0.76 ALDH1A1 (0.50) ARCRBNNPC1RAB9AKMT2A
SCHEMBL28367550 0.76 ACHE (0.50) ACHEPOLBNPC1RAB9AKMT2A
SCHEMBL30753697 0.76 ALDH1A1 (0.50) ACHEPOLBNPC1RAB9AKMT2A
SCHEMBL1409365 0.75 AR (0.40) ARCRBNMAP1LC3BMAP1LC3AHTR2C
SCHEMBL19277082 0.75 CRBN (0.46) ARCRBNDDB1MAP1LC3BMAP1LC3A
SCHEMBL709584 0.74 ACHE (0.48) ACHEPOLBNPC1RAB9AKMT2A
SCHEMBL29722802 0.74 ACHE (0.48) ACHEPOLBNPC1RAB9AKMT2A
SCHEMBL12538455 0.74 ENPP2 (0.41) ARMAP1LC3BMAP1LC3AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10544124-B2 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-01-28 US disclosed
US-20190047982-A1 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190047982-A1 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides DDT, CYP4X1, CYP4Z1 AR 3988/4885CRBN 2187/4885DDB1 3794/4885
US-10544124-B2 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides DDT, CYP4X1, CYP4Z1 AR 3988/4885CRBN 2187/4885DDB1 3794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.