SCHEMBL20739664

SCHEMBL20739664

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc5c4oc4c(-c6cc7ccccc7c7ccccc67)cccc45)n3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
HPGD P15428 5/20 0.40
MAPT P10636 5/20 0.40
KDM4E B2RXH2 4/20 0.40
TSHR P16473 3/20 0.40
MAPK1 P28482 2/20 0.40
HSD17B10 Q99714 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ATM Q13315 2/20 0.40
TP53 P04637 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GPR84 Q9NQS5 2/20 0.40
CYP11B1 P15538 1/20 0.39
CASP1 P29466 1/20 0.37
HIF1A Q16665 1/20 0.37
ADORA3 P0DMS8 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24217268 0.97 ALDH1A1 (0.42) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL24475243 0.96 ALDH1A1 (0.41) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL22889330 0.89 ALOX5 (0.45) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL20739774 0.88 CYP11B1 (0.40) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL22889384 0.88 ALOX5 (0.47) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL22889378 0.88 ALOX5 (0.44) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL23822450 0.87 ALOX5 (0.38) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL24217269 0.87 ALDH1A1 (0.44) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL24525894 0.87 ALDH1A1 (0.44) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL24216935 0.87 ALDH1A1 (0.44) ALDH1A1HPGDMAPTKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11802123-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2023-10-31 US disclosed
US-11802123-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2023-10-31 US disclosed
US-20220064153-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2022-03-03 US disclosed
US-11208402-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2021-12-28 US disclosed
US-20190047991-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11802123-B2 Heterocyclic compound and organic light emitting device comprising the same CRY1, CRY2, PPOX ALDH1A1 76/4885HPGD 686/4885MAPT 775/4885
US-11208402-B2 Heterocyclic compound and organic light emitting device comprising the same CRY1, CRY2, PPOX ALDH1A1 76/4885HPGD 686/4885MAPT 775/4885
US-20190047991-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, ORC3 ALDH1A1 176/4885HPGD 1840/4885MAPT 1216/4885
US-20220064153-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, ORC3 ALDH1A1 94/4885HPGD 1729/4885MAPT 699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.