Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.45 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790975 | 0.87 | KMT5A (0.42) | L3MBTL3KMT5ACHRM1HRH3ALDH1A1 | |
| SCHEMBL20744455 | 0.87 | L3MBTL3 (0.46) | L3MBTL3KMT5ACHRM1GNAI3GNAO1 | |
| SCHEMBL25389420 | 0.79 | DPP7 (0.34) | HSD11B1 | |
| SCHEMBL29678691 | 0.78 | HSD11B1 (0.40) | L3MBTL3HSD11B1CHRM2MEN1CYP2D6 | |
| SCHEMBL25426783 | 0.76 | HSD11B1 (0.41) | L3MBTL3CHRM1HSD11B1CHRM2MEN1 | |
| SCHEMBL25427337 | 0.76 | HSD11B1 (0.41) | L3MBTL3CHRM1HSD11B1CHRM2MEN1 | |
| SCHEMBL29143116 | 0.76 | HSD11B1 (0.44) | L3MBTL3HSD11B1GNAI3GNAO1GNAI1 | |
| SCHEMBL25429104 | 0.76 | HSD11B1 (0.41) | L3MBTL3CHRM1HSD11B1CHRM2MEN1 | |
| SCHEMBL15948708 | 0.76 | CHRNB2 (0.47) | L3MBTL3KMT5ACHRM1HRH3CHRM2 | |
| SCHEMBL12505797 | 0.74 | KMT5A (0.41) | L3MBTL3KMT5ACHRM1HRH3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668882-A1 | PYRROLO[2,3-B]PYRIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019034890-A1 | PYRROLO[2,3-B]PYRIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2019-02-21 | — | — | WO | disclosed |