SCHEMBL20747503

SCHEMBL20747503

C=Nc1cc(C)ccc1C=C(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.39
KDM4E B2RXH2 7/20 0.39
LMNA P02545 3/20 0.39
HTT P42858 3/20 0.39
SLC9A3 P48764 2/20 0.37
SLC9A1 P19634 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
DHODH Q02127 1/20 0.33
ALDH1A1 P00352 4/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
PABPC1 P11940 1/20 0.32
FTO Q9C0B1 1/20 0.32
POLB P06746 2/20 0.31
GAA P10253 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24073150 0.77 ALDH1A1 (0.46) MAPTKDM4ELMNAHTTSLC9A3
SCHEMBL21499260 0.76 MAPT (0.36) MAPTKDM4ELMNAHTTNPC1
SCHEMBL18570253 0.75 CA12 (0.35) MAPTKDM4ELMNAHTTRAB9A
SCHEMBL9550627 0.74 TDP1 (0.44) MAPTKDM4ELMNAHTTSLC9A3
SCHEMBL24402173 0.73 SLC9A3 (0.42) MAPTKDM4ELMNAHTTSLC9A3
SCHEMBL11402271 0.72 TRPA1 (0.50) MAPTKDM4ELMNAHTTSLC9A3
SCHEMBL22334417 0.71 GABRA1 (0.66) MAPTKDM4ELMNASLC9A3SLC9A1
SCHEMBL15919037 0.71 ALDH1A1 (0.48) MAPTKDM4ELMNASLC9A3SLC9A1
SCHEMBL15919038 0.71 GABRA1 (0.40) MAPTKDM4ELMNAHTTSLC9A3
SCHEMBL20663341 0.70 RAB9A (0.57) MAPTNPC1RAB9AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10208026-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208026-B2 Organic electroluminescent materials and devices ZYX, LBR, LOXL1 MAPT 4119/4885KDM4E 3364/4885LMNA 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.