Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TKT | P29401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475136 | 0.78 | — | — | |
| SCHEMBL31094645 | 0.76 | LTB4R (0.32) | LTB4R | |
| SCHEMBL4584887 | 0.75 | SLC6A3 (0.37) | LTB4RALDH1A1TKT | |
| SCHEMBL5481203 | 0.75 | ALDH1A1 (0.49) | ALDH1A1TKT | |
| SCHEMBL2093318 | 0.74 | — | — | |
| SCHEMBL13845083 | 0.74 | — | — | |
| SCHEMBL2488428 | 0.72 | LTB4R (0.33) | LTB4RALDH1A1TKT | |
| SCHEMBL2095755 | 0.71 | — | — | |
| SCHEMBL5198891 | 0.71 | ALDH1A1 (0.35) | ALDH1A1TKT | |
| SCHEMBL7805091 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038362-A1 | ANTIBACTERIAL PYRROLOIMIDAZOLONES | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-02-28 | — | — | WO | disclosed |