Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239448 | 0.80 | HTR2A (0.45) | HTR2AKDM4ECYP2D6LMNATP53 | |
| SCHEMBL2830663 | 0.67 | HTR2C (0.37) | HTR2AKDM4ECYP2D6LMNATP53 | |
| SCHEMBL20765492 | 0.67 | HTR2A (0.41) | HTR2AKDM4ECYP2D6LMNATP53 | |
| SCHEMBL30483496 | 0.66 | HTR2A (0.34) | HTR2A | |
| SCHEMBL28839808 | 0.66 | HTR2A (0.34) | HTR2A | |
| SCHEMBL2290547 | 0.65 | HTR2A (0.39) | HTR2AKDM4ECYP2D6LMNATP53 | |
| SCHEMBL11875463 | 0.64 | BRD4 (0.53) | HTR2AKDM4ECYP2D6LMNATP53 | |
| SCHEMBL6055955 | 0.63 | HTR2C (0.40) | HTR2AKDM4ECYP2D6LMNATP53 | |
| SCHEMBL11884483 | 0.63 | HTR2A (0.37) | HTR2AKDM4ECYP2D6LMNATP53 | |
| SCHEMBL27520400 | 0.62 | SIGMAR1 (0.33) | HTR2AKDM4ECYP2D6LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111247157-B | Novel transition metal compound, catalyst composition comprising the same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin using the same | 沙特基础工业爱思开NEXLENE私人有限公司 | 2023-03-28 | — | — | CN | disclosed |
| US-11339230-B2 | Transition metal compound, catalyst composition including the same, and method for preparing ethylene homopolymer or copolymer of ethylene and α-olefin using the same | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2022-05-24 | — | — | US | disclosed |
| US-20210139617-A1 | NOVEL TRANSITION METAL COMPOUND, CATALYST COMPOSITION INCLUDING THE SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND ALPHA-OLEFIN USING THE SAME | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2021-05-13 | — | — | US | disclosed |
| CN-111247157-A | Novel transition metal compound, catalyst composition comprising the same, and method for preparing ethylene homopolymer or copolymer of ethylene and α -olefin using the same | 沙特基础工业爱思开NEXLENE私人有限公司 | 2020-06-05 | — | — | CN | disclosed |
| WO-2019038605-A1 | NOVEL TRANSITION METAL COMPOUND, CATALYST COMPOSITION INCLUDING THE SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND α-OLEFIN USING THE SAME | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2019-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139617-A1 | NOVEL TRANSITION METAL COMPOUND, CATALYST COMPOSITION INCLUDING THE SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND ALPHA-OLEFIN USING THE SAME | NOTUM, ALOX12, ETFA | HTR2A 4375/4885KDM4E 3020/4885CYP2D6 2643/4885 |
| US-11339230-B2 | Transition metal compound, catalyst composition including the same, and method for preparing ethylene homopolymer or copolymer of ethylene and α-olefin using the same | NOTUM, ALOX12, ETV6 | HTR2A 4415/4885KDM4E 3142/4885CYP2D6 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.