SCHEMBL207657

SCHEMBL207657

O=C(O)Cc1ccc(B(O)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.58
CAMK2A Q9UQM7 1/20 0.58
AKR1B1 P15121 1/20 0.56
LMNA P02545 2/20 0.54
GAA P10253 2/20 0.54
TSHR P16473 2/20 0.54
ABCC4 O15439 1/20 0.54
PTGS1 P23219 1/20 0.54
HTT P42858 1/20 0.54
LPL P06858 2/20 0.52
LIPG Q9Y5X9 2/20 0.52
TRPV1 Q8NER1 4/20 0.51
F11 P03951 1/20 0.50
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
FFAR1 O14842 1/20 0.48
POLB P06746 2/20 0.47
NSD2 O96028 1/20 0.47
GRK2 P25098 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28457631 0.89 LPL (0.47) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL69614 0.83 CA2 (0.79) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL14756837 0.80 LPL (0.56) CA2LPLLIPGTRPV1F11
SCHEMBL3782177 0.80 CA2 (0.59) CA2LPLLIPGTRPV1F11
Hydrochloric Acid SCHEMBL25180348 0.80 CA2 (0.75) CA2CAMK2AAKR1B1LMNAGAA
Hydrochloric Acid SCHEMBL6765874 0.80 CA2 (0.75) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL6240012 0.79 CA2 (0.50) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL363489 0.78 FFAR1 (0.61) CA2LPLLIPGTRPV1FFAR1
SCHEMBL28983973 0.77 CA2 (0.58) CA2CAMK2AAKR1B1LMNAGAA
Phenylacetic Acid SCHEMBL10587458 0.76 AKR1B1 (0.85) CA2CAMK2AAKR1B1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720728-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME Alcon Inc. (CH) 2026-04-08 EP claimed
US-20240393501-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME ALCON INC (CH) 2024-11-28 US claimed
WO-2024241239-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME ALCON INC. (CH) 2024-11-28 WO claimed
US-11931454-B2 Wet-packed soft hydrogel ocular inserts ALCON INC. (CH) 2024-03-19 US claimed
CN-115959993-A Synthetic method of 2-aryl propionic acid compound 山东中医药大学 2023-04-14 CN claimed
CN-114727954-A Wet packed soft hydrogel ocular inserts 爱尔康公司 2022-07-08 CN claimed
EP-4017478-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS Alcon Inc. (CH) 2022-06-29 EP claimed
EP-3746820-B1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON ALCON INC (CH) 2022-02-16 EP claimed
CN-111146496-B Polymer electrolyte and lithium ion battery containing same 珠海冠宇电池股份有限公司 2021-07-13 CN claimed
EP-3840637-A1 MEDIATED DRUG RELEASE FOR REDUCING IN VIVO ANALYTE INDICATOR DEGRADATION Senseonics, Incorporated (US) 2021-06-30 EP claimed
WO-2021053586-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS ALCON INC. (CH) 2021-03-25 WO claimed
US-20210077385-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS ALCON INC. (CH) 2021-03-18 US claimed
EP-3746820-A1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON Alcon Inc. (CH) 2020-12-09 EP claimed
CN-111566517-A Contact lenses having lubricious coating thereon 爱尔康公司 2020-08-21 CN claimed
CN-111514312-A Polypeptide drug conjugate for promoting nerve regeneration and application thereof 南通大学 2020-08-11 CN claimed
CN-111146496-A Polymer electrolyte and lithium ion battery containing same 珠海冠宇电池有限公司 2020-05-12 CN claimed
WO-2020041240-A1 MEDIATED DRUG RELEASE FOR REDUCING IN VIVO ANALYTE INDICATOR DEGRADATION SENSEONICS, INCORPORATED (US) 2020-02-27 WO claimed
US-20200054251-A1 MEDIATED DRUG RELEASE FOR REDUCING IN VIVO ANALYTE INDICATOR DEGRADATION SENSEONICS, INCORPORATED (US) 2020-02-20 US claimed
US-20190235277-A1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON ALCON INC. (CH) 2019-08-01 US claimed
EP-1674581-A1 Twin probes, a tool for the detection of SNPs Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2006-06-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210077385-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS BRI3BP, BRWD1, HRH2 CA2 2295/4885CAMK2A 4388/4885AKR1B1 1595/4885
US-20200054251-A1 MEDIATED DRUG RELEASE FOR REDUCING IN VIVO ANALYTE INDICATOR DEGRADATION SLC2A1, SLC2A4, SLC2A8 CA2 196/4885CAMK2A 3197/4885AKR1B1 624/4885
US-11931454-B2 Wet-packed soft hydrogel ocular inserts BRI3BP, BRWD1, HRH2 CA2 2295/4885CAMK2A 4388/4885AKR1B1 1595/4885
US-20240393501-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME CRYAB, P4HB, ILK CA2 2744/4885CAMK2A 4495/4885AKR1B1 1653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.