Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727368 | 0.92 | CASP3 (0.49) | KMT2AMEN1SMN1; SMN2ADORA1NPSR1 | |
| SCHEMBL17629577 | 0.90 | MAPT (0.42) | KMT2AMEN1CYP2C19SMN1; SMN2ADORA1 | |
| SCHEMBL1586711 | 0.84 | CASP3 (0.49) | KMT2AMEN1SMN1; SMN2ADORA1NPSR1 | |
| SCHEMBL6304400 | 0.82 | ACHE (0.49) | CASP3ESR2GPR119NR1H2ACHE | |
| SCHEMBL13488441 | 0.82 | CXCR3 (0.43) | KMT2AMEN1SMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL13488374 | 0.81 | ALDH1A1 (0.49) | KMT2AMEN1SMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL14920289 | 0.80 | CHRM5 (0.50) | ADORA1ESR2GPR119NR1H2 | |
| SCHEMBL5927238 | 0.79 | ADORA1 (0.46) | KMT2AMEN1SMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL6868401 | 0.76 | ADORA1 (0.56) | KMT2AMEN1SMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL21047249 | 0.76 | ADORA1 (0.43) | KMT2AMEN1ADORA1TSHRESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040106-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |