Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19041058 | 0.85 | HTT (0.51) | MAPK1ALDH1A1LMNAKDM4E | |
| SCHEMBL20767219 | 0.85 | LMNA (0.63) | MAPK1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL3964758 | 0.83 | LMNA (0.68) | MAPK1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL19041065 | 0.80 | LMNA (0.49) | MAPK1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL20767253 | 0.79 | ALDH1A1 (0.57) | MAPK1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL1042337 | 0.77 | ACHE (0.51) | MAPK1KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL12880486 | 0.77 | LOXL2 (0.46) | ALDH1A1POLBLMNAHTR2AMAOB | |
| Hydrochloric Acid SCHEMBL1169438 | 0.75 | LOXL2 (0.45) | MAPK1ALDH1A1POLBLMNAHTR2A | |
| SCHEMBL7038204 | 0.75 | KMT2A (0.50) | KMT2AMEN1POLBLMNAFAAH | |
| SCHEMBL17481411 | 0.75 | PPARA (0.53) | KMT2AMEN1LMNAPPARAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040105-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |
| WO-2019040105-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |