Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20779077 | 0.91 | PARP1 (0.40) | KIF11PARP1PARP10TDP2NOTUM | |
| SCHEMBL19645932 | 0.82 | HTR2A (0.49) | PDK2HTR2AHTR2C | |
| SCHEMBL26375448 | 0.76 | KIF11 (0.49) | PDK2KIF11HTR2AHSP90AA1MCL1 | |
| SCHEMBL15945815 | 0.74 | PDK2 (0.37) | PDK2KIF11MCL1PIK3CAPIK3CB | |
| SCHEMBL10057836 | 0.74 | PDK2 (0.37) | PDK2KIF11NPBWR1 | |
| SCHEMBL19085025 | 0.73 | PDK2 (0.61) | PDK2HTR2AHTR2CPARP1SLC6A4 | |
| SCHEMBL23586953 | 0.73 | TDP2 (0.39) | KIF11PARP1PARP10TDP2 | |
| SCHEMBL13694202 | 0.73 | MAOA (0.52) | KIF11HSP90AA1MCL1PARP1PARP10 | |
| SCHEMBL19292554 | 0.72 | HTR2A (0.42) | PDK2HTR2AHTR2CCNR1CNR2 | |
| SCHEMBL4158192 | 0.71 | CYP3A4 (0.48) | KIF11NFE2L2NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043140-A1 | CROSSLINKABLE FLUORINATED POLY(ARYLENE ETHER) | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2019-03-07 | — | — | WO | disclosed |