Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | CCND1 | P24385 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20779762 | 0.80 | OPRK1 (0.43) | — | |
| SCHEMBL20767455 | 0.79 | BRD4 (0.41) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL20779572 | 0.79 | ALDH1A1 (0.37) | CDK2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL1528439 | 0.78 | ADRA1A (0.50) | LRRK2LMNAKDM4EMAPTMEN1 | |
| SCHEMBL20779695 | 0.75 | OPRK1 (0.46) | — | |
| SCHEMBL20779692 | 0.75 | LATS1 (0.43) | CDK1CDK2ALDH1A1KDM4EMAPT | |
| SCHEMBL20779774 | 0.74 | ROCK2 (0.39) | LRRK2MEN1KMT2AADORA2AADORA1 | |
| SCHEMBL20779889 | 0.74 | OPRK1 (0.35) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL20779751 | 0.73 | KDM4E (0.38) | CDK1CDK4CCNB1CCNA2CCND1 | |
| SCHEMBL21925800 | 0.72 | MAPT (0.51) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040380-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2019-02-28 | — | — | WO | disclosed |