Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24635669 | 0.85 | KEAP1 (0.41) | MAPTHTTTAAR1ALDH1A1LMNA | |
| SCHEMBL24635258 | 0.81 | MAPT (0.42) | MAPTHTTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL14930874 | 0.80 | ALDH1A1 (0.50) | MAPTHTTNPC1RAB9AP2RX7 | |
| SCHEMBL20780229 | 0.78 | MAPT (0.47) | MAPTHTTNPC1RAB9AP2RX7 | |
| SCHEMBL24635574 | 0.78 | ALDH1A1 (0.41) | MAPTHTTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL23774851 | 0.77 | MAPT (0.45) | MAPTHTTNPC1RAB9AP2RX7 | |
| SCHEMBL11598415 | 0.76 | SIGMAR1 (0.55) | TAAR1NPC1RAB9A | |
| SCHEMBL23747256 | 0.76 | MAPT (0.44) | MAPTHTTNPC1RAB9AP2RX7 | |
| SCHEMBL13626615 | 0.76 | KDM4E (0.48) | MAPTHTTNPC1RAB9AP2RX7 | |
| SCHEMBL245209 | 0.74 | MAPT (0.50) | MAPTHTTNPC1RAB9AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145546-A1 | PROCESS FOR SYNTHESIZING 2-BROMOLYSERGIC ACID DIETHYLAMIDE VIA CONTROLLED BROMINATION OF LYSERGIC ACID | CERUVIA LIFESCIENCES LLC (US) | 2024-07-04 | — | — | WO | disclosed |