Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PNLIP | P16233 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24379800 | 0.82 | MEN1 (0.54) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL26542645 | 0.77 | HDAC1 (0.33) | PLAUPLGEP300KMT2AF10 | |
| SCHEMBL16371053 | 0.75 | MAPT (0.41) | ALDH1A1MAPTTDP1EP300KMT2A | |
| SCHEMBL20786981 | 0.74 | MITF (0.42) | ALDH1A1MAPTPLAUPLGEP300 | |
| SCHEMBL26543681 | 0.73 | PLG (0.38) | ALDH1A1MAPTTDP1PLAUPLG | |
| SCHEMBL26544759 | 0.73 | NPC1 (0.34) | ALDH1A1MAPTPLAUPLGEP300 | |
| SCHEMBL24379797 | 0.72 | EP300 (0.53) | ALDH1A1MAPTTDP1EP300KMT2A | |
| SCHEMBL26544999 | 0.72 | PLG (0.37) | ALDH1A1MAPTTDP1PLAUPLG | |
| SCHEMBL16392463 | 0.71 | EP300 (0.57) | EP300KMT2AMEN1LMNARAB9A | |
| SCHEMBL21063938 | 0.71 | MAPT (0.53) | ALDH1A1MAPTTDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038405-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-02-28 | — | — | WO | disclosed |