Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 4/20 | 0.46 |
| ▸ | EIF4E | P06730 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20788515 | 0.83 | FYN (0.53) | FYNPARP1CHEK2NPC1RAB9A | |
| SCHEMBL20788527 | 0.75 | MAPT (0.57) | FYNKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20788518 | 0.72 | ABCB1 (0.61) | KMT2ASMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL29950282 | 0.72 | LMNA (0.54) | EIF4ECDC7LMNAMAPTHTT | |
| SCHEMBL995083 | 0.72 | LMNA (0.54) | EIF4ECDC7LMNAMAPTHTT | |
| SCHEMBL27647715 | 0.71 | BCAT2 (0.53) | EIF4ECDC7KMT2ALMNAMAPT | |
| SCHEMBL4268078 | 0.71 | SMN1; SMN2 (0.53) | KMT2ASMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL25295556 | 0.70 | ALDH1A1 (0.52) | FYNCDC7CHEK2KMT2ASMN1; SMN2 | |
| SCHEMBL28081760 | 0.69 | ALDH1A1 (0.47) | AKR1B10AKR1B1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL26343197 | 0.69 | DTYMK (0.50) | AKR1B10AKR1B1AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190076552-A1 | Precursor of a histone deacetylase inhibitor PET imaging compound for tracking cerebral neurodegenerative and tumor diseases | INSTITUTE OF NUCLEAR ENERGY RESEARCH, NUCLEAR ENERGY COUNCIL, EXECUTIVE YUAN (TW) | 2019-03-14 | — | — | US | claimed |
| US-10507250-B2 | Precursor of a histone deacetylase inhibitor PET imaging compound for tracking cerebral neurodegenerative and tumor diseases | INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN (TW) | 2019-12-17 | — | — | US | disclosed |
| US-20190076552-A1 | Precursor of a histone deacetylase inhibitor PET imaging compound for tracking cerebral neurodegenerative and tumor diseases | INSTITUTE OF NUCLEAR ENERGY RESEARCH, NUCLEAR ENERGY COUNCIL, EXECUTIVE YUAN (TW) | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10507250-B2 | Precursor of a histone deacetylase inhibitor PET imaging compound for tracking cerebral neurodegenerative and tumor diseases | H1-3, H1-2, HDAC2 | FYN 3784/4885EIF4E 4465/4885CDC7 2175/4885 |
| US-20190076552-A1 | Precursor of a histone deacetylase inhibitor PET imaging compound for tracking cerebral neurodegenerative and tumor diseases | H1-3, H1-2, HDAC2 | FYN 3784/4885EIF4E 4465/4885CDC7 2175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.