Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | CDC7 | O00311 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995083 | 1.00 | LMNA (0.54) | LMNAMAPTHTTCTSDCDC7 | |
| SCHEMBL27705000 | 0.86 | KEAP1 (0.51) | LMNAMAPTHTTCTSDCDC7 | |
| SCHEMBL115478 | 0.85 | CTSD (0.65) | LMNAMAPTHTTCTSDALDH1A1 | |
| SCHEMBL10766788 | 0.85 | CTSD (0.65) | LMNAMAPTHTTCTSDALDH1A1 | |
| SCHEMBL10752700 | 0.84 | ALDH1A1 (0.51) | LMNAMAPTALDH1A1TDP1TSHR | |
| SCHEMBL2362519 | 0.84 | CDC7 (0.46) | LMNAMAPTHTTCTSDCDC7 | |
| SCHEMBL4439669 | 0.84 | TSHR (0.59) | LMNAMAPTHTTCTSDALDH1A1 | |
| Hydrochloric Acid SCHEMBL10550781 | 0.83 | CTSD (0.62) | LMNAMAPTHTTCTSDALDH1A1 | |
| Hydrochloric Acid SCHEMBL8025084 | 0.83 | CTSD (0.62) | LMNAMAPTHTTCTSDALDH1A1 | |
| SCHEMBL15741933 | 0.82 | TSHR (0.54) | LMNAMAPTHTTCTSDCDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-109836378-B | Sphingomyelin synthase inhibitor, preparation method and application thereof | 上海华汇拓医药科技有限公司 | 2022-09-30 | — | — | CN | disclosed |