Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12326181 | 0.74 | MAOA (0.53) | ALDH1A1KDM4EMAPTHPGDMAOA | |
| SCHEMBL1680715 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTSMN1; SMN2MAOA | |
| SCHEMBL2093994 | 0.72 | MAOA (0.51) | ALDH1A1KDM4EMAPTHPGDMAOA | |
| SCHEMBL30136447 | 0.71 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2RAB9AGAA | |
| SCHEMBL24049723 | 0.71 | PGR (0.56) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL294721 | 0.71 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2RAB9AGAA | |
| SCHEMBL7293492 | 0.71 | PDE4A (0.69) | ALDH1A1KDM4EMAPTCYP3A4KMT2A | |
| SCHEMBL20550260 | 0.71 | PTPRC (0.54) | ALDH1A1KDM4ESMN1; SMN2MAOAMAOB | |
| SCHEMBL1673262 | 0.71 | PTGDR2 (0.58) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL29572032 | 0.71 | KDM4E (0.64) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11299484-B2 | Inhibiting fatty acid synthase (FASN) | FORMA THERAPEUTICS, INC. (US) | 2022-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11299484-B2 | Inhibiting fatty acid synthase (FASN) | FASN, SCD, FADS1 | ALDH1A1 1168/4885KDM4E 3899/4885MAPT 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.