Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3084431 | 0.80 | TAAR1 (0.61) | TAAR1L3MBTL1LMNAADRB2HPGD | |
| SCHEMBL20796240 | 0.77 | TAAR1 (0.53) | TAAR1L3MBTL1LMNACYP2D6HPGD | |
| SCHEMBL30666100 | 0.76 | HTT (0.53) | TAAR1L3MBTL1LMNAADRB2HIF1A | |
| SCHEMBL25588044 | 0.76 | HTT (0.53) | TAAR1L3MBTL1LMNAADRB2HIF1A | |
| SCHEMBL19080589 | 0.75 | TAAR1 (0.55) | TAAR1L3MBTL1HPGDSIGMAR1KMT2A | |
| SCHEMBL16789643 | 0.71 | ALDH1A1 (0.42) | L3MBTL1LMNACYP2D6SIGMAR1KMT2A | |
| SCHEMBL19505482 | 0.70 | SIGMAR1 (0.81) | ADRB2SLC6A2SLC6A4OPRM1ADRB1 | |
| SCHEMBL8442802 | 0.70 | L3MBTL1 (0.67) | TAAR1L3MBTL1LMNACYP2D6HPGD | |
| SCHEMBL31008662 | 0.70 | LMNA (0.38) | LMNAADRA1A | |
| SCHEMBL681435 | 0.69 | TAAR1 (1.00) | TAAR1L3MBTL1LMNAHIF1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043642-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2019-03-07 | — | — | WO | disclosed |