Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21799762 | 0.90 | TPSAB1 (0.39) | ALDH1A1LMNAMAPK1NPSR1HTT | |
| SCHEMBL14748112 | 0.90 | SIGMAR1 (0.55) | ALDH1A1LMNAMAPK1NPSR1HTT | |
| SCHEMBL13813305 | 0.90 | SIGMAR1 (0.55) | ALDH1A1LMNAMAPK1NPSR1HTT | |
| SCHEMBL18811757 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP2D6KDM4EMEN1KMT2A | |
| SCHEMBL21799796 | 0.77 | NOS1 (0.38) | ALDH1A1CYP2D6SIGMAR1SMN1; SMN2MEN1 | |
| SCHEMBL10943350 | 0.76 | SIGMAR1 (0.54) | ALDH1A1HTTCYP2D6CYP2C19SIGMAR1 | |
| SCHEMBL15336915 | 0.72 | SIGMAR1 (0.55) | ALDH1A1LMNAMAPK1NPSR1HTT | |
| SCHEMBL3271284 | 0.72 | SIGMAR1 (0.48) | ALDH1A1LMNAMAPK1NPSR1HTT | |
| SCHEMBL21799495 | 0.71 | PNMT (0.34) | ALDH1A1LMNAMAPK1HTTCYP1A2 | |
| SCHEMBL20796231 | 0.71 | TAAR1 (0.52) | LMNACYP2D6SIGMAR1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150159123-A1 | COMPOSITIONS FOR ANTI PATTERN COLLAPSE TREATMENT COMPRISING GEMINI ADDITIVES | BASF SE (DE) | 2015-06-11 | — | — | US | disclosed |