Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2079716 | 1.00 | TSHR (0.53) | TSHRMAPK1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL14375069 | 1.00 | TSHR (0.53) | TSHRMAPK1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL40329 | 0.81 | ALDH1A1 (0.59) | TSHRMAPK1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL79163 | 0.77 | DTYMK (0.62) | TSHRMAPK1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL16956717 | 0.77 | TSHR (0.58) | TSHRMAPK1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6156834 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL6156831 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL339922 | 0.76 | ALDH1A1 (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6395556 | 0.76 | ALDH1A1 (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL1138798 | 0.76 | DTYMK (0.60) | TSHRMAPK1ALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906538-B2 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |
| US-20080262048-A1 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2008-10-23 | — | — | US | disclosed |
| EP-1799636-B1 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | SCHERING PLOUGH LTD (CH) | 2008-08-27 | — | — | EP | disclosed |
| US-7312248-B2 | Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1799636-A2 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | Schering-Plough Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006034333-A2 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | SCHERING-PLOUGH LTD. (CH) | 2006-03-30 | — | — | WO | disclosed |
| US-20060063841-A1 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH LTD. (CH) | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063841-A1 | Parasiticides; nematocides; crop protection | TRHDE, DDT, EPHX1 | TSHR 1334/4885MAPK1 3689/4885ALDH1A1 4339/4885 |
| US-20080262048-A1 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | TRHDE, EPX, EPHX1 | TSHR 414/4885MAPK1 3695/4885ALDH1A1 3635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.