Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20799747 | 0.95 | GABRA2 (0.50) | GABRA2GABRB2SMN1; SMN2MAPTTSHR | |
| SCHEMBL20806387 | 0.90 | TSHR (0.49) | SMN1; SMN2MAPTTSHRHSD17B10RAB9A | |
| SCHEMBL20799792 | 0.89 | TP53 (0.51) | GABRA2GABRB2SMN1; SMN2MAPTTSHR | |
| SCHEMBL20806394 | 0.89 | ALDH1A1 (0.49) | GABRA2GABRB2SMN1; SMN2MAPTTSHR | |
| SCHEMBL24633216 | 0.88 | GABRA2 (0.44) | GABRA2GABRB2SMN1; SMN2MAPTTSHR | |
| SCHEMBL4276707 | 0.87 | TSHR (0.54) | GABRA2GABRB2SMN1; SMN2MAPTTSHR | |
| SCHEMBL20806414 | 0.86 | TSHR (0.50) | SMN1; SMN2MAPTTSHRHSD17B10RAB9A | |
| SCHEMBL20806416 | 0.85 | CYP1A2 (0.48) | GABRA2GABRB2SMN1; SMN2MAPTTSHR | |
| SCHEMBL20806332 | 0.84 | KDM4E (0.49) | SMN1; SMN2MAPTTSHRHSD17B10RAB9A | |
| SCHEMBL20806424 | 0.84 | RAB9A (0.49) | SMN1; SMN2MAPTTSHRHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230329092-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| EP-3679023-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-11-02 | — | — | EP | disclosed |
| WO-2019048458-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230329092-A1 | MATERIALS FOR ELECTRONIC DEVICES | SOD1, GPX1, EFNA1 | GABRA2 2487/4885GABRB2 2257/4885SMN1; SMN2 2490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.