Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 3/20 | 0.69 |
| ▸ | GSK3B | P49841 | 3/20 | 0.69 |
| ▸ | CMA1 | P23946 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226680 | 0.83 | CMA1 (0.76) | GSK3AGSK3BCMA1MAPTTP53 | |
| SCHEMBL3384174 | 0.83 | GSK3A (1.00) | GSK3AGSK3BCMA1MAPTCHRM5 | |
| SCHEMBL140975 | 0.79 | MGLL (0.72) | GSK3AGSK3BCMA1MAPTLMNA | |
| SCHEMBL3381344 | 0.77 | GSK3A (1.00) | GSK3AGSK3BCMA1MGLLHSP90AA1 | |
| SCHEMBL22402810 | 0.75 | TUBB4A (0.51) | NR1H3 | |
| SCHEMBL4949653 | 0.74 | TAAR1 (0.67) | NR1H3NR1H2 | |
| SCHEMBL21348197 | 0.73 | GSK3A (0.68) | GSK3AGSK3BCMA1MAPTCHRM5 | |
| SCHEMBL17123192 | 0.72 | GSK3A (0.66) | GSK3AGSK3BCMA1MAPTCHRM5 | |
| SCHEMBL1542663 | 0.72 | HSP90AA1 (0.71) | GSK3AGSK3BMAPTTP53LMNA | |
| SCHEMBL7224723 | 0.72 | MGLL (0.60) | GSK3AGSK3BMAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089962-B1 | RADIOIODINATED COMPOUNDS | NUTECH VENTURES (US) | 2019-03-13 | — | — | EP | disclosed |