Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8166237 | 0.81 | — | — | |
| SCHEMBL1226464 | 0.75 | LMNA (0.38) | POLBOPRM1LMNAMAPK1HTT | |
| SCHEMBL21728779 | 0.75 | ALDH1A1 (0.33) | POLBLMNAMAPK1HTT | |
| SCHEMBL19533158 | 0.75 | LMNA (0.38) | POLBOPRM1LMNAMAPK1HTT | |
| SCHEMBL43433 | 0.74 | — | — | |
| SCHEMBL2222242 | 0.74 | ALDH1A1 (0.37) | NOS2POLBHTT | |
| SCHEMBL32667642 | 0.74 | ALDH1A1 (0.37) | NOS2POLBHTT | |
| SCHEMBL2150283 | 0.74 | ALDH1A1 (0.37) | NOS2POLBHTT | |
| SCHEMBL926765 | 0.73 | THRA (0.38) | POLBOPRM1LMNAHTT | |
| SCHEMBL16787518 | 0.73 | NOS2 (0.54) | NOS2LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019051396-A1 | SMALL MOLECULE INHIBITORS OF EBOLA AND LASSA FEVER VIRUSES AND METHODS OF USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-03-14 | — | — | WO | disclosed |