SCHEMBL20809062

SCHEMBL20809062

CC(C)(C)Cc1ccc2ccc(-c3ccccc3)nc2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.42
NPC1 O15118 5/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
SMN1; SMN2 Q16637 5/20 0.41
CYP3A4 P08684 3/20 0.41
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
THPO P40225 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
HSD17B10 Q99714 1/20 0.41
AR P10275 2/20 0.40
IGF1R P08069 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809063 0.89 PSMB5 (0.44) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL20809047 0.85 IGF1R (0.40) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL20809295 0.85 GRM2 (0.44) RAB9ANPC1SMN1; SMN2KDM4ETP53
SCHEMBL20809294 0.84 ESR1 (0.34) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL25777087 0.80 NPC1 (0.35) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL29746219 0.79 AR (0.46) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL398104 0.79 AR (0.46) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL601707 0.79 TAAR1 (0.47) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL20809321 0.78 DHODH (0.51) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL23898441 0.76 TDP1 (0.48) RAB9ANPC1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 RAB9A 4437/4885NPC1 3375/4885MEN1 4264/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 RAB9A 4437/4885NPC1 3375/4885MEN1 4264/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 RAB9A 3706/4885NPC1 2038/4885MEN1 3319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.