SCHEMBL20809294

SCHEMBL20809294

Cc1cc(C)cc(-c2ccc3ccc(CC(C)(C)C)cc3n2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.34
CYP1A2 P05177 1/20 0.33
IGF1R P08069 1/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 3/20 0.32
ALDH1A1 P00352 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
GMNN O75496 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
THPO P40225 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809064 0.89 ESR1 (0.38) ESR1CYP1A2MAPT
SCHEMBL20809295 0.88 GRM2 (0.44) NPC1RAB9AKDM4ESMN1; SMN2TP53
SCHEMBL20809329 0.85 CDK9 (0.34) CYP1A2IGF1RCDK9DYRK1ADYRK2
SCHEMBL4444081 0.84 NOS3 (0.37) CYP1A2NPC1RAB9ASMN1; SMN2TP53
SCHEMBL20809062 0.84 RAB9A (0.42) CYP1A2IGF1RNPC1RAB9AMEN1
SCHEMBL24795834 0.84 SLC22A12 (0.32) IGF1R
SCHEMBL4436058 0.80 DHODH (0.39) CYP1A2NPC1RAB9AMEN1KMT2A
SCHEMBL20809325 0.80 CDK9 (0.36) CYP1A2IGF1RCDK9DYRK1ADYRK2
SCHEMBL20809065 0.79 GRM2 (0.43) NPC1RAB9ASMN1; SMN2TP53GRM2
SCHEMBL13989404 0.78 CYP1A2 (0.55) ESR1CYP1A2NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402877-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-22 US disclosed
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 ESR1 3459/4885CYP1A2 857/4885IGF1R 2991/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 ESR1 3459/4885CYP1A2 857/4885IGF1R 2991/4885
US-20220402877-A1 ELECTROLUMINESCENT DEVICE MCOLN2, MCOLN1, LDHB ESR1 375/4885CYP1A2 2194/4885IGF1R 4712/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 ESR1 1921/4885CYP1A2 422/4885IGF1R 2828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.